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Medicine composition for treating cardiovascular and cerebrovascular diseases

A technology for cardiovascular and cerebrovascular diseases and a composition, which is applied in the field of pharmaceutical compositions and can solve the problems of less maple syrup and the like

Inactive Publication Date: 2006-10-25
JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Liquidambar is rarely used clinically, and is mainly used for trauma, carbuncle, swelling and pain, hematemesis, epistaxis, and traumatic bleeding. So far, there has been no medicine for treating cardiovascular and cerebrovascular diseases using liquidambar extract as an active ingredient and other auxiliary materials. combination

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 Liquidambar gum extract preparation:

[0036] Liquidambar balm 5kg, add 5-10% dilute hydrochloric acid and evenly, stand still for 1-3 hours, supercritical CO 2 Extraction, extraction temperature 20-40°C, pressure 14-16Pa, extraction 20-50min, to get oily liquid, then add 100-500ml ethanol as entrainer, extraction temperature 45°C, pressure 15-17Pa, extract decompression to recover ethanol, The resultant is uniformly mixed with the above-mentioned oily substance to obtain the active extract of sweetgum gum containing volatile oil, organic acid and resin.

Embodiment 2

[0037] Embodiment 2 Liquidambar gum extract preparation:

[0038] Liquidambar gum 5kg, add 6% dilute hydrochloric acid and evenly, stand still for 1.5 hours, supercritical CO 2 Extraction, the extraction temperature is 30°C, the pressure is 15Pa, and the extraction is 30min to obtain an oily liquid, then add 200ml of ethanol as an entrainer, the extraction temperature is 45°C, the pressure is 16Pa, the extract is decompressed to recover ethanol, and the obtained product is mixed with the above oily liquid evenly, that is The active extract of sweetgum balm containing volatile oil, organic acid and resin is obtained.

Embodiment 3

[0039] The preparation of embodiment 3 soft capsules

[0040] Liquidambar gum extract 300g is pressed into 1000 soft capsules by a soft capsule machine.

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PUM

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Abstract

The present invention relates to a Chinese medicine prepared by using dried resin extract of liquidamber formosana as effective component and its application for preventing and curing angiocardiopathy and cerebrovascular disease.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a traditional Chinese medicine composition prepared by extracting and processing dry resin of sweetgum gum, and its application in preventing and treating cardiovascular and cerebrovascular diseases. Background technique [0002] The background of the present invention comes from the relevant literature records to Styrax and Liquidambar. [0003] Cardiovascular and cerebrovascular diseases have high morbidity and mortality in the population, seriously endangering human health and affecting people's quality of life. Cardiovascular and cerebrovascular diseases, the main diseases are hypertension, coronary heart disease, cerebral infarction and cerebral hemorrhage. In western developed countries, cardiovascular and cerebrovascular diseases have become the leading cause of death. In my country, the incidence of cardiovascular and cerebrovascular diseases is ...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P9/10A61P9/12
Inventor 许向阳杨士豹袁源檀爱民刘春晖
Owner JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD
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