Suppository of Metronidazole and preparation technique

Abstract

A Shuangzuotai suppository is prepared proportionally from metronidazole, mycosporin, chlorhexidine acetate, matrix, cotton suppository saturated by said matrix, and a tubular band made of PVC or PE.

Description

technical field [0001] The invention relates to a suppository and a preparation process thereof, in particular to a Shuangzotai suppository and a preparation method thereof, belonging to the field of medicine and hygiene. Background technique [0002] Shuangzotai suppository is a commonly used over-the-counter drug for gynecology. Generally, each tablet contains 0.2g of metronidazole, 0.16g of clotrimazole, and 8mg of chlorhexidine acetate. Shuangzoltaijian is an antibacterial drug, suitable for bacterial vaginosis, fungal vaginitis, trichomonal vaginitis and mixed infectious vaginitis. The auxiliary materials in the preparation process are mainly excipient semi-synthetic fatty acid ester, paraffin wax and softener lanolin. [0003] The Shuangzotai suppository sold in the market is carrier-free. Like other suppositories, the melted suppository cannot be fully absorbed by the body in time. During use, due to the outflow of the drug and the matrix, it will pollute the clothes...

AI Technical Summary

Problems solved by technology

However, the drug suppository containing tampons does have a soft suppository material, and it is easy to cause the suppository to be difficult to form during the embolization process and cannot be used.

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