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Formula of making hollow capsule and its preparation method

A technology of hollow capsules and formulations, which is applied in capsule delivery, pharmaceutical formulations, drug delivery, etc. It can solve the problems of performance gap and high cost, and achieve the effects of excellent quality indicators, reduced manufacturing costs, and unlimited application of people

Inactive Publication Date: 2005-06-08
ZHEJIANG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the invention patent with the patent application number 02134750.6 and the name "A Starch Empty Capsule and Its Production Process", a hollow capsule made of starch or starch derivatives and its preparation method are mentioned. As a raw material, the cost is still high, even higher than that of gelatin; while ordinary starch is used as a raw material, its performance is far behind that of potato starch

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Add 420 grams of tapioca starch to 1 liter of deionized water, stir to dissolve, and filter; add 10 g of carrageenan to 1 liter of deionized water, stir to dissolve, and filter; combine with starch solution, stir well, gelatinize in a water bath at 85°C, add Sodium dodecylsulfonate 0.5g, glycerin 10mL, stir evenly, dip in glue. It can be manually dipped in glue or mechanically dipped in glue, baked at 38-40°C for 1 hour, degummed, and hollow capsules are obtained.

Embodiment 2

[0033] Add 360 grams of potato starch to 1 liter of deionized water, stir to dissolve, and filter; add 15 g of carrageenan to 1 liter of deionized water, stir to dissolve, and filter; combine with starch solution, stir well, gelatinize in a 95°C water bath, add Sodium dodecylsulfonate 0.5g, glycerin 10mL, stir evenly, dip in glue. It can be manually dipped in glue or mechanically dipped in glue, baked at 38-40°C for 1 hour, degummed, and hollow capsules are obtained.

Embodiment 3

[0035] Add 350 grams of sweet potato starch to 1 liter of deionized water, stir to dissolve, and filter; add 10 g of carrageenan to 1 liter of deionized water, stir to dissolve, and filter; combine with the starch solution, stir well, gelatinize in a 90°C water bath, add Sodium dodecylsulfonate 0.5g, glycerin 10mL, stir evenly, dip in glue. It can be manually dipped in glue or mechanically dipped in glue, baked at 38-40°C for 1 hour, degummed, and hollow capsules are obtained.

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PUM

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Abstract

A hollow capsule is prepared from purified water, potato starch, carragheenin, surfactant and plasticizer. Its preparing process is also disclosed. Its advantages are high quality and low cost.

Description

(1) Technical field [0001] The invention relates to a formula for making hollow capsules, in particular to a formula of hollow capsules with potato starch as raw material and a preparation method thereof. (2) Background technology [0002] At present, the hollow capsules used are all made of gelatin. Gelatin capsules generally have good performance, but moisture has a great influence on them. When the air humidity is high, the capsules become soft, and when the air is dry, the capsules become brittle, which seriously affects the use. Because gelatin is to be raw material production with pig bone and pig skin, make gelatin be that the suitable crowd of capsule of raw material is limited. The price of gelatin is much higher than that of starch, and the price of gelatin used to make empty capsules is generally 6 to 8 times that of starch. [0003] In the invention patent with the patent application number 02134750.6 and the name "A Starch Empty Capsule and Its Production Proce...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J3/07A61K9/48
Inventor 钱俊青唐振兴
Owner ZHEJIANG UNIV OF TECH
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