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Naodesheng soft capsule and its preparation method

A raw soft and capsule technology, which is applied in capsule delivery, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of easy pollution, affecting the absorption of active ingredients, and inconvenience for patients to take and accept honeyed pills, so as to be easy for the human body Absorb and overcome the effect of large loss of active ingredients

Inactive Publication Date: 2005-01-05
韩昌栓
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional Naodesheng preparations are mostly honeyed pills, tablets, capsules, and granules. Honeyed pills are not convenient for patients to take and accept, and have poor absorption in the body. Crude drug powder is directly used as medicine, which is easy to pollute, has poor stability, and is difficult to store
Tablets, capsules, and granules also contain crude drug powder, which is not conducive to microbial control and affects the absorption of active ingredients
At present, there is no manufacturing method for extracting effective ingredients from the five medicinal materials and no Naodesheng finished products with stable quality.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] First, prepare the five-flavored Chinese medicine raw materials according to the ratio:

[0026] Notoginseng 78g Chuanxiong 78g Pueraria 261g

[0027] Hawthorn 157g, safflower 91g.

[0028] The production method is as follows:

[0029] Crush the three cuts into coarse powder, add 10 times of 80% ethanol for percolation, collect the percolation liquid, recover ethanol from the percolation liquid under reduced pressure, concentrate it into a thick paste, and vacuum dry it below 85°C to form a dry paste for later use; the second step Add Pueraria root, hawthorn, and safflower to 10 times of water and decoct for 1 hour, filter, add medicinal residues to 8 times of water and decoct twice, each time for 1 hour, filter, combine and concentrate the three filtrates to a relative density of 1.10 (50 ℃), add ethanol alcohol precipitation (alcohol precipitation concentration 70%), the supernatant decompresses to recover ethanol, concentrates into a thick paste, and va...

Embodiment 2

[0031] Get extract 70g, corn oil 120g, other are with embodiment 1.

Embodiment 3

[0033] Get extract 100g, corn oil 150g, aluminum stearate 2g, beeswax 2g, other are with embodiment 1.

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PUM

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Abstract

A softcapsule 'Naodesheng' is prepared from notoginseng, Chuan-xiong rhizome, pueraria root, haw and safflower through respective extracting, removing impurities, concentrating, drying proportional mixing, adding plant oil and dissolving-suspending air and die pressing or dripping.

Description

technical field [0001] The invention relates to Naodesheng Soft Capsule, which can refresh the brain, dredge meridians, promote blood circulation and remove blood stasis, and mainly treat cerebral arteriosclerosis, ischemic stroke and sequelae of cerebral hemorrhage, etc., and a preparation method thereof. Background technique [0002] Naodesheng Tablets and Naodesheng Pills are included in the "Chinese Pharmacopoeia" 2000 edition. They are national essential medicines. Differentiation of its blood stasis" ("Materia Medica Seeking Truth"), safflower "good at tongli meridians" ("Drugs and Chemicals"), "curing silence and blood knots" ("Tang Materia Medica"), the combination of the two drugs can promote blood circulation Dispelling blood stasis, dredging meridians and activating collaterals, all are monarch drugs; Chuanxiong "blood qi medicine", promoting blood circulation and promoting qi, drawing medicine from the meridian to the disease place, is a minister medicine; kudzu ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61P9/10
Inventor 韩昌栓
Owner 韩昌栓
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