Medicine for regulating immunity and its production method

A technology of immunomodulatory drugs and medicinal materials, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., can solve problems such as unreasonable formulas and inaccurate drug effects, and achieve good preventive effects, reliable curative effects, and combination party novel effect

Inactive Publication Date: 2003-04-16
金陵药业股份有限公司技术中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The technical problem to be solved by the present invention is that the formula of the existing immunoregulatory drugs is not reasonable enough, and the drug effect is not accurate enough, so as to provide people with a new immunomodulatory drug with reliable drug effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] First, weigh the raw materials according to the following ratio:

[0020] Lycium barbarum 50Kg, astragalus 35Kg, safflower 15Kg.

[0021] Next, process according to the following steps:

[0022] 1. After mixing the above-mentioned three medicinal materials, add 10 times (weight ratio, the same below) amount of water to soak, fry for 1.5 hours, and add 8 times the amount of water for 1.0 hour;

[0023] 2. Merge two decoctions and concentrate to contain 1g crude drug per ml;

[0024] 3. Add ethanol to make the alcohol content reach 50%, and let stand for 8 hours;

[0025] 4. Carry out centrifugation on a butterfly centrifuge, the centrifuge speed is 5000rpm, and centrifuge for 20 minutes in total;

[0026] 5. Take the supernatant, recover the ethanol until the relative density is 1.25 (measured at 80°C), and obtain the extract;

[0027] 6. Add 106Kg of lactose, 42.5Kg of dextrin, and 1.5Kg of flavoring agent to the obtained extract in a ratio of 5:2:0.05 to granulate,...

Embodiment 2

[0030] First, weigh the raw materials according to the following ratio:

[0031] Lycium barbarum 40Kg, astragalus 50Kg, safflower 10Kg.

[0032] Next, process by the method described in embodiment 1, its difference is as follows:

[0033] 1. Add 12 times the amount of water for 2 hours for the first decoction, and add 10 times the amount of water for 1.5 hours for the second time.

[0034] 2. Combine the decoctions, concentrate them to contain 1g of crude drug per ml, add ethanol to make the alcohol content reach 45%, and let stand for 10 hours;

[0035] 3. During centrifugation, the centrifuge speed is 6000rpm, and the centrifugation is for 30 minutes;

[0036] 4. Recover ethanol to a relative density of 1.35 (measured at 80°C).

[0037] 5. Add 99Kg of lactose, 49.5Kg of dextrin and 1.5Kg of flavoring agent to the obtained extract in a ratio of 6:3:0.1.

[0038] Finally, quantitative subpackaging and sealing are carried out to obtain finished granules.

Embodiment 3

[0040] First, weigh the raw materials according to the following ratio:

[0041] Lycium barbarum 60Kg, astragalus 35Kg, safflower 5Kg.

[0042] Next, process by the method described in embodiment 1, its difference is as follows:

[0043] 1. Add 8 times the amount of water for 1 hour for the first decoction, and add 6 times the amount of water for 0.5 hours for the second time.

[0044] 2. Combine the decoctions, concentrate to contain 1g of crude drug per ml, add ethanol to make the alcohol content reach 30%, and let stand for 12 hours;

[0045] 3. During centrifugation, the centrifuge speed is 7000rpm, and the centrifugation is for 40 minutes;

[0046] 4. Recover ethanol to a relative density of 1.40 (measured at 80°C)

[0047] 5. Add 99Kg of lactose, 49.4Kg of dextrin and 1.6Kg of flavoring agent to the above-mentioned extract according to the ratio of 8:4:0.15.

[0048] Finally, quantitative subpackaging and sealing are carried out to obtain finished granules.

[0049]...

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Abstract

A Chinese medicine in the form of granules for immunoregulation is prepared from wolfberry fruit (1-97 %), astragalus root (1-97%) and safflower (1-97%) through mixing, decocting twice, merging decoctions, concentrating, adding alcohol, laying aside for 8-12 hr, centrifugal separation of supernatant, recovering alcohol, preparing extract, adding lactose, dextrin and flavouring, granulating then drying and sieving. Its advantages are sure curative effect, low cost, and no toxic by-effect.

Description

technical field [0001] The invention relates to a medicine with immune regulating function, in particular to an immune regulating medicine made from medicinal and edible herbal medicines as raw materials. technical background [0002] At present, there are still many problems in the production enterprises of immunomodulatory drugs in our country, the most typical of which are the repeated products and low technological content. Even hundreds of companies produce the same product at the same time and imitate each other. Most of the immunomodulatory drugs on the market now belong to the first generation of traditional tonics, the formula is not reasonable enough, and it is difficult to make an exact evaluation of the efficacy. Therefore, there is an urgent need to develop novel immunomodulatory drugs with reasonable formula and definite efficacy to meet people's daily consumption needs. Contents of the invention ...

Claims

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Application Information

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IPC IPC(8): A61P37/02
Inventor 卞家驹徐向阳万辉张庆晓陈钟倪洁张杰王兴旺
Owner 金陵药业股份有限公司技术中心
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