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Composition and pharmaceutical preparation thereof

A technology of pharmaceutical preparations and compositions, applied in the field of compositions and pharmaceutical preparations

Pending Publication Date: 2022-05-13
津药达仁堂集团股份有限公司第六中药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The present invention studies the properties of ferulic acid and ligustilide separately and in combination, and finds that the two have a vasodilation effect respectively, and the combination of the two has a synergistic effect, which has not been reported in the existing literature

Method used

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  • Composition and pharmaceutical preparation thereof
  • Composition and pharmaceutical preparation thereof
  • Composition and pharmaceutical preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0136] The composition contains ferulic acid and Z-ligustilide, and the weight ratio of the two is:

[0137] Ferulic acid: Z-ligustilide = 1:4.

[0138] The composition is obtained by mixing ferulic acid and Z-ligustilide, or by mixing the extract of traditional Chinese medicine containing ferulic acid and the extract of traditional Chinese medicine containing Z-ligustilide, or by co-extracting Angelica sinensis and Rhizoma Chuanxiong get.

Embodiment 2

[0140] The composition contains ferulic acid and Z-ligustilide, and the weight ratio of the two is:

[0141] Ferulic acid: Z-ligustilide = 1:5

[0142] The composition is obtained by mixing ferulic acid and Z-ligustilide, or by mixing the extract of traditional Chinese medicine containing ferulic acid and the extract of traditional Chinese medicine containing Z-ligustilide, or by co-extracting Angelica sinensis and Rhizoma Chuanxiong get.

Embodiment 3

[0144] The composition contains ferulic acid and Z-ligustilide, and the weight ratio of the two is:

[0145] Ferulic acid: Z-ligustilide = 1:6

[0146] The composition is obtained by mixing ferulic acid and Z-ligustilide, or by mixing the extract of traditional Chinese medicine containing ferulic acid and the extract of traditional Chinese medicine containing Z-ligustilide, or by co-extracting Angelica sinensis and Rhizoma Chuanxiong get.

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Abstract

The invention relates to a composition and a pharmaceutical preparation thereof, the composition contains ferulic acid and ligustilide, the weight ratio of ferulic acid to Z-ligustilide is 1: (4-10), or ferulic acid to Z-ligustilide is 1: 4, or ferulic acid to Z-ligustilide is 1: 10, or ferulic acid to Z-ligustilide is 1: 9.43, and the composition can also contain senkyunolide I, (-)-apigenyl lactide, or (-)-apigenyl lactide, or (-)-apigenyl lactide, or (-)-apigenyl lactide, or (-)-apigenyl lactide, or (-)-apigenyl lactide, or (-)-apigenyl lactide. And senkyunolide H. The composition is prepared from the following components in percentage by weight: 1-10

Description

technical field [0001] The invention relates to a composition and a pharmaceutical preparation thereof, particularly a drop pill preparation, which has the effect of treating headache, dizziness, stroke, dim vision, forgetfulness and insomnia. Background technique [0002] It is known that many traditional Chinese medicines have the effects of regulating qi and activating blood circulation, removing blood stasis and relieving pain. As the disclosed dropping pill of State Food and Drug Administration National Drug Standard YBZ00432005-2009Z. [0003] Chinese patent 97105810.5 discloses a dripping pill containing Rhizoma Chuanxiong and Angelica ether extracts and a preparation method thereof. The preparation process disclosed in its embodiment is as follows: take 50% each of Rhizoma Chuanxiong and Angelica coarse powder, mix evenly, use 95% ethanol as solvent, completely soak the coarse powder in ethanol, and after soaking for 24 hours, slowly percolate to percolate The liqu...

Claims

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Application Information

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IPC IPC(8): A61K31/365A61P29/00A61P25/28A61P25/20A61P25/00A61P9/10A61P9/04A61P1/08A61K31/192A61K31/201A61K31/20
CPCA61K31/192A61K31/365A61K31/201A61K31/20A61P29/00A61P25/28A61P25/20A61P25/00A61P9/10A61P9/04A61P1/08A61K2300/00Y02A50/30
Inventor 周鸿刘丹刘彤王金磊
Owner 津药达仁堂集团股份有限公司第六中药厂
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