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Stereotactic fixing frame for hillock hemorrhage biological experiment

A biological experiment, stereotaxic technology, applied in veterinary instruments, animal restraint instruments, medical science, etc., can solve the problems of slow drug absorption, accelerated blood circulation, difficult to clean, etc., to speed up the expulsion movement and increase the storage space. , easy to take effect

Inactive Publication Date: 2022-04-12
HENAN CANCER HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In view of the above situation, in order to overcome the defects of the prior art, the present invention provides a stereotaxic fixed frame for biological experiments of thalamic hemorrhage, which effectively solves the problem that the mice absorb the medicine slowly after injecting the medicine to the mice, and increases the driving force. The function of exercising mice to speed up blood circulation in the experiment has achieved the purpose of immobilizing the mice and performing tail vein injection, achieving the purpose of automatically raising the surgical instruments when the mice need to be operated, and optimizing the The fixing method of the mouse torso optimizes the fixing structure of the mouse head, which is convenient for the medical staff to take the surgical instruments, solves the problem that the experimental place is not easy to clean up after the experiment, and adds the ability to disinfect the device function to facilitate the discharge of sewage

Method used

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  • Stereotactic fixing frame for hillock hemorrhage biological experiment
  • Stereotactic fixing frame for hillock hemorrhage biological experiment
  • Stereotactic fixing frame for hillock hemorrhage biological experiment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment one, by Figure 1-6 Provided, the present invention includes a box body 1, in order to achieve the purpose of helping the mice to absorb the medicine after injecting the medicine for the experiment, the inside of the box body 1 is fixedly connected with a bottom plate 2, and the upper side of the bottom plate 2 is fixedly connected with a A rotating shell 3, the interior of the rotating shell 3 is provided with a liftable operating panel 4, the upper side of the bottom plate 2 is rotatably connected with a power rod 5, and the operating plate 4 can slide up and down along the power rod 5, the The bottom of the power rod 5 is fixedly connected with a rotating frame 6, and the left side of the rotating frame 6 is fixedly connected with a driving plate 7, and the left side of the rotating shell 3 is provided with a first runway chamber 8 fixedly connected with the bottom plate 2, The right side of described rotary housing 3 is provided with a second runway cavit...

Embodiment 2

[0046] Embodiment two, on the basis of embodiment one, by Figure 3-5 with Figure 13-14 Provided, in order to achieve the purpose of automatically raising the surgical instrument when the mouse needs to be operated, a rotating slideway 27 is provided inside the rotating shell 3, and the left and right sides of the operating panel 4 are fixedly connected with A sliding block 28, each sliding block 28 can slide along the rotating slideway 27, the sliding block 28 rotates along the rotating slideway 27 so as to realize the up and down movement of the operating panel 4, and a plurality of up and down sliding grooves are provided on the power rod 5 29. The operating panel 4 can slide along the upper and lower chute 29, and the upper side of the rotating shell 3 is provided with a plurality of left and right chute 30, and each cover plate 10 can slide along the left and right chute 30, and the operation panel The upper side of 4 is rotatably connected with a connecting block 31, a...

Embodiment 3

[0049] Embodiment three, on the basis of embodiment one, by Figure 2-3 with Figure 8 Provided, in order to achieve the purpose of raising and fixing the mouse, each of the limiting mechanisms 24 includes a limiting plate 251 that can slide up and down along the second fixing plate 12, and the injection table 14 is connected to the anatomical Table 16 is all connected with the corresponding limit plate 251 in rotation, each limit plate 251 is provided with a toothed plate 252 that can slide back and forth, and the front side of each toothed plate 252 is fixedly connected with multiple A limit spring 253, a limit handle 254 is fixedly connected to the right side of each toothed plate 252, and a limit lever 255 is fixedly connected to the left side of each toothed plate 252;

[0050] The inside of each second fixing plate 12 is provided with a limit chute 38, each of the limit chute 251 can slide up and down along the limit chute 38, each limit chute 38 is fixed A toothed bel...

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Abstract

A three-dimensional positioning fixing frame for a hillock hemorrhage biological experiment effectively solves the problem that a mouse absorbs medicine slowly after the mouse is injected with the medicine and comprises a box body, a bottom plate is fixedly connected to the interior of the box body, a rotating shell is arranged on the upper side of the bottom plate, an operation plate is arranged in the rotating shell, and a power rod is arranged on the upper side of the bottom plate. A rotating frame is arranged on the lower side of the power rod, a driving plate is arranged on the left side of the rotating frame, a first runway cavity is formed in the left side of a rotating shell, a second runway cavity is formed in the right side of the rotating shell, a cover plate is arranged on the upper side of the rotating shell, first fixing plates are fixedly connected to the front side and the rear side of the rotating shell, and second fixing plates are arranged on the front side and the rear side of the rotating shell. By means of the design, the function of driving an experimental mouse to move so as to accelerate blood circulation is effectively added, the purposes of fixing the mouse and conducting intravenous injection on the tail are achieved, and the problem that an experimental site is not easy to clean after an experiment is conducted is solved.

Description

technical field [0001] The invention belongs to the technical field of medical experimental equipment, and in particular relates to a stereotaxic fixing frame for biological experiments of thalamic hemorrhage. Background technique [0002] The thalamus, also known as the dorsal thalamus, is the largest oval gray matter nucleus in the diencephalon. It is located on both sides of the third ventricle. The left and right thalamus are connected by a gray matter mass (called the middle block). The thalamus is the high-level sensory center. It is the most important sensory conduction relay station. In clinical medicine, the influence of different drugs on the thalamus is a very important topic. In academic research, mice are usually used as experimental samples, and usually pre-venously administered to mice. Injection, and then create a mouse thalamic hemorrhage, dissect the mouse and study and analyze the specific cells or tissues in the brain, but because of the experimental proc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D7/00A61D3/00A61L2/18
Inventor 张震张书玮张馨丹李喜龙卢锡华
Owner HENAN CANCER HOSPITAL
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