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Essence lotion composition containing lipidosome with skin brightening and whitening effects and a preparation method of the essence lotion composition

A technology of composition and liposome, which is applied in the field of daily chemicals, can solve problems such as large differences in physical and chemical properties of functional ingredients, unsatisfactory skin brightening and whitening effects, and single functional ingredients, so as to improve uneven skin tone and inhibit melanin The formation and the effect of expanding the scope of application

Active Publication Date: 2021-11-30
湖北省麦诗特生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most functional cosmetic products currently on the market have a single functional ingredient or the physical and chemical properties of different functional ingredients vary greatly, resulting in poor compatibility and poor transdermal absorption.
When the functional ingredients are difficult to enter the target site and the target cells work, it will lead to unsatisfactory skin brightening and whitening effects

Method used

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  • Essence lotion composition containing lipidosome with skin brightening and whitening effects and a preparation method of the essence lotion composition
  • Essence lotion composition containing lipidosome with skin brightening and whitening effects and a preparation method of the essence lotion composition
  • Essence lotion composition containing lipidosome with skin brightening and whitening effects and a preparation method of the essence lotion composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0090] A kind of essence milk composition containing skin-lightening and whitening efficacy liposome, and its raw material component proportion content is as shown in Table 1 below.

Embodiment 1

[0093] Embodiment 1 The preparation technology of the essence milk containing liposome with brightening and whitening effect, comprises the following steps:

[0094] 1) Preparation of liposomes with skin-lightening and whitening effects: Dissolve 1000 mg of lecithin in 10 mL of ethanol, stir until fully dissolved, and then transfer to a rotary evaporator. A uniform lecithin film was formed on the wall of the container; 20 mL of phosphate buffered solution was mixed with 665 mg of white willow bark extract, 333 mg of undecylenoyl phenylalanine, 665 mg of nicotinamide, and 665 mg of pine algae extract. The mixed solution was transferred to the container of the rotary evaporator, and the lecithin film was hydrated for 20 minutes. After the film completely fell off, ultrasonication was carried out for 3 minutes to obtain skin-brightening and whitening liposomes; the particle size was 0.1-1 micron.

[0095] 2) Wetting and dispersing the thickener in water completely to obtain a mix...

Embodiment 2

[0098] Embodiment 2 The preparation technology of the liposome essence milk containing skin-lightening and whitening effect, comprises the steps:

[0099] 1) Preparation of liposomes with skin-lightening and whitening effects: Dissolve 1200 mg of lecithin in 15 mL of ethanol, stir until fully dissolved, and then transfer to a rotary evaporator. A uniform lecithin film was formed on the wall of the container; 25 mL of phosphate buffer solution was mixed with 515 mg of white willow bark extract, 257 mg of undecylenoyl phenylalanine, 515 mg of nicotinamide, and 515 mg of pine algae extract. The mixed solution was transferred to the container of the rotary evaporator, and the lecithin film was hydrated for 30 minutes. After the film completely fell off, ultrasonication was performed for 5 minutes to obtain the skin-brightening and whitening effect liposomes; the particle size was 0.1-1 micron.

[0100] 2) Wetting and dispersing the thickener in water completely to obtain a mixed s...

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Abstract

The invention discloses an essence lotion composition containing lipidosome with skin brightening and whitening effects and a preparation method of the essence lotion composition. The essence lotion composition contains the following raw material components: 1.0%-45.0% of lipidosome with skin brightening and whitening effects, 5.0%-40.0% of emollient, 0.5%-30.0% of emulsifier, 0.5%-20.0% of filler, 0.1%-10.0% of thickener, 0.3%-5.0% of preservative, 0.01%-5% of pH regulator, 0.01%-1.0% of daily essence and the balance deionized water. The lipidosome with the skin brightening and whitening effects comprises the following main functional components: a white willow bark extract, undecylenoyl phenylalanine, nicotinamide and a codium fragile extract. The multiple different functional components are subjected to transdermal co-delivery through the lipidosome, and multi-effect and multi-target whitening synergistic interaction can be realized in the aspects of inhibiting generation, transportation, metabolism and the like of melanin.

Description

technical field [0001] The invention relates to a skin care product and a preparation method thereof, belonging to the technical field of daily chemicals, and more particularly to a liposome essence milk composition with whitening and skin-brightening effects and a preparation method thereof. Background technique [0002] Nowadays, people's pursuit of whitening has never stopped. Whitening can prevent dull skin and make skin refreshed and translucent. Although we can temporarily whiten our skin tone through some makeup creams, liquid foundations, loose powders, etc., we hope that our own skin tone can be fair, which can also reduce some of the burden of cosmetics on the skin. So how to effectively whiten skin care is also a problem that people are constantly exploring at this stage. [0003] Recently, many companies have developed some whitening skin care product compositions to achieve whitening effect by interfering with the production, transport and accumulation of melan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9722A61K8/67A61K8/44A61K8/14A61Q19/02
CPCA61K8/9789A61K8/9722A61K8/675A61K8/44A61K8/14A61Q19/02A61K2800/782A61K2800/592
Inventor 杨帆周紫燕李沫郭苗周正郭阳
Owner 湖北省麦诗特生物科技有限公司
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