Application of andrographolide in preparation of product for promoting browning of white adipose

Abstract

The invention relates to the technical field of medicine application of natural products, in particular to novel application of andrographolide in preparation of a product for promoting browning of white adipose. The andrographolide activates and converts white adipose tissues of energy storage tissues into brown adipose tissues for energy metabolism, activates the functions of brown adipose, improves the activity of the brown adipose, promotes conversion of the adipose into heat energy for dissipation, keeps the energy balance of a body, and also has the effects of regulating the adipose distribution of the body, reducing the total adipose weight and reducing the body weight. Therefore, the andrographolide, extract containing andrographolide or a preparation of the andrographolide has wide application prospects in regulating adipose distribution and preventing or treating obesity-related metabolic diseases.

Description

technical field [0001] The present invention relates to a drug, health food or food additive capable of activating peroxisome proliferator-activated receptor α (PPARα) and promoting the browning of white fat, in particular to a traditional Chinese medicine Andrographis paniculata in promoting the browning of white fat applications in related products. Background technique [0002] Lipometabolic disorders are characteristic pathological changes of metabolic syndromes such as obesity, type 2 diabetes, fatty liver and other diseases. Patients with lipid metabolism disorders have abnormal storage of triglycerides in adipose tissue, which leads to lipid deposition in different parts of the body and gradually leads to insulin resistance. With the increasing and lower utilization of fat, the adipose tissue will gradually increase, leading to the formation of obesity. With the development of the economy and the change of technology, the obesity rate in more and more countries is s...

AI Technical Summary

Problems solved by technology

[0009] At present, andrographolide promotes the browning of white fat, regulates body fat distributio

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