Cell irreversible electroporation device and cell irreversible electroporation method

Abstract

The invention provides a cell irreversible electroporation device. The cell irreversible electroporation device comprises an electroporation mechanism, a medicine supply mechanism and a power supply mechanism, wherein the electroporation mechanism comprises at least two conductive needle bodies; each conductive needle body is provided with a first cavity as well as a first opening and a second opening which are used for communicating the first cavity with the outside; the medicine supply mechanism is connected with the conductive needle bodies and is used for conveying medicine molecules to the first cavities of the conductive needle bodies; and the power supply mechanism is connected with the electroporation mechanism and is used for providing an electric field for enabling cells to generate irreversible electroporation for the electroporation mechanism. According to the cell irreversible electroporation device provided by the invention, an anti-cancer medicine is combined with the locally applied irreversible electroporation electric field, so that tumor cells can be efficiently killed and the tumor treatment effect is effectively improved; the dosage of the anti-cancer medicine is further reduced and toxic and side effects on bodies, caused by the anti-cancer medicine, are alleviated; and the cell irreversible electroporation device has a relatively good application prospect in the field of cancer treatment.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a cell irreversible electroporation device and a cell irreversible electroporation method. Background technique [0002] Tumor is a disease that seriously threatens human health. It is formed by continuous excessive proliferation of cells, and has the characteristics of invasion to surrounding tissues and metastasis to other organs. Tumor seriously endangers human health and is one of the public health problems recognized in the world today. At present, tumor treatment methods mainly include surgery, radiation therapy, chemotherapy and immunotherapy. Chemotherapy is the use of chemical drugs that can kill tumor cells to treat tumors. Through oral administration, intramuscular injection or intravenous injection, some drug molecules can reach the lesion through the internal circulation of the body and kill cancer cells. [0003] Chemotherapy allows the drug to reach the l...

AI Technical Summary

Problems solved by technology

[0004] Therefore, the technical problem to be solved by the present invention is to overcome the defects in the prior art that tumor cells cannot absorb drugs for a long time by electrochemotherapy, resulting in limited killing effect on tumor cells and toxic side effects on normal tissues.

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