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Composition comprising combination of red clover extract and hops extract for improvement of menopausal disorder

A technology of red clover and its extract is applied in the field of compositions comprising a combination of red clover extract and hop extract for improving menopausal diseases, which can solve problems such as pulmonary thromboembolism and side effects, and achieve the effect of improving menopausal diseases

Inactive Publication Date: 2021-08-06
自然科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] To improve these menopausal diseases, hormone therapy has been used to supplement the lack of estrogen, but long-term use has caused uterine cancer, breast cancer, stroke, pulmonary thromboembolism and various side effects

Method used

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  • Composition comprising combination of red clover extract and hops extract for improvement of menopausal disorder
  • Composition comprising combination of red clover extract and hops extract for improvement of menopausal disorder
  • Composition comprising combination of red clover extract and hops extract for improvement of menopausal disorder

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0075] Preparation Example 1: Preparation of Red Clover Extract

[0076] The red clover powder was pulverized by a grinder, and then reflux extracted twice at 70° C. for 4 hours using 10 L of 60% alcohol (Daehan Alcohol Life Co., Ltd., Korea) to extract 1 kg of raw material. The extract was filtered under reduced pressure through filter paper (ADVANTEC 2, 280 mm, China), the filtrate was concentrated in vacuo (rotavaper R-220SE, BUCHI, Switzerland), and dried in a desiccator (Daeil Engineering, Korea) to obtain the Extract.

preparation example 2

[0077] Preparation example 2: preparation of hop extract

[0078] 10 L of 70% alcohol was used for reflux extraction twice at 70° C. for 4 hours to extract 1 kg of well-dried hop flowers and buds. The extract was filtered through filter paper, and the filtrate was concentrated in vacuo and dried in a desiccator to obtain the extract in powder form.

preparation example 3

[0079] Preparation Example 3: Preparation of combination of red clover extract and hop extract

[0080] The red clover extract and the hop extract respectively obtained in Preparation Example 1 and Preparation Example 2 were mixed in a weight ratio of 2:1 or 3:1 to prepare a combination of the red clover extract and the hop extract. These combinations were used for efficacy evaluation in the in vitro and in vivo tests described below.

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Abstract

The present invention relates to a composition for improving female climacteric (menopausal) disorder, comprising a combination of a red clover extract and a hops extract as an active ingredient. More specifically, the present invention relates to a food composition for improving female climacteric diseases or a pharmaceutical composition for preventing or treating female climacteric diseases, and a method for preparing the composition for improving female climacteric diseases, wherein the composition comprises the combination of the red clover extract and the hops extract as an active ingredient.

Description

technical field [0001] The present invention relates to a composition for improving women's climacteric (menopausal) diseases, which comprises a combination of red clover extract and hops extract as active ingredients, and more specifically, relates to a A food composition for improving women's menopausal disorder or a pharmaceutical composition for preventing or treating women's menopausal disorder, and a method for preparing the composition for improving women's menopausal disorder, wherein the composition comprises Combination of red clover extract and hop extract as active ingredients. [0002] This research was financially supported by the Ministry of Small, Medium and Small Enterprises and Entrepreneurship (MSS) under the Regional Specialized Industry Development Program (R&D, P0003019) under the supervision of the Korea Institute of Technology Advancement (KIAT). Background technique [0003] Menopause is the interruption of menstruation that occurs when a woman's ge...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61K36/60A61P5/24A23L33/105
CPCA23L33/105A61K36/48A61P5/24A23V2002/00A61K36/185A61K2236/00A23V2200/302A61K2300/00A61K36/60A61P5/30A61K2236/15A61K2236/51A61K2236/53
Inventor 李映澈柳守烈刘寿显金贤珍全洗英李保树金美灿李延濬
Owner 自然科技有限公司
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