An ultrasonic drug delivery device for lens dyeing low-temperature separation fluid in smile surgery

A drug delivery device and ultrasonic technology, applied in the field of ophthalmic refractive surgery, can solve the problems of difficult separation of corneal stroma lens, wrong lens shovel entry, tearing of corneal incision, etc., to alleviate secondary mechanical effects, reduce resistance, and reduce mechanical The effect of pulling and friction

Active Publication Date: 2022-04-12
SHENZHEN HOSPITAL OF SOUTHERN MEDICAL UNIV
View PDF10 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Especially limited by the biomechanical conditions of the cornea, the surgical sequence must first separate the upper surface of the corneal stroma lens, and then separate the lower surface of the corneal stroma lens. Once the order is wrong or the lens separation technique is improperly operated, it is easy to cause the lens shovel to enter the wrong layer or Separation of the interlayer, resulting in difficulty in separation of the corneal stromal lens, breakage, damage to the corneal cap (cap) and tearing of the corneal incision, etc., which in turn lead to clinical complications of varying degrees

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • An ultrasonic drug delivery device for lens dyeing low-temperature separation fluid in smile surgery
  • An ultrasonic drug delivery device for lens dyeing low-temperature separation fluid in smile surgery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] It should be noted that, in the embodiment of the present application, OBL (opaque bubble layers) refers to the aggregates of bubbles gathered between the corneal layers, and is the water vapor generated when the femtosecond laser explodes in the tissue. and CO 2 Formed by the diffusion of gaps between collagen fibers above or below the cutting plane, it is an undesirable clinical phenomenon that occurs during femtosecond laser corneal surgery.

[0019] In the embodiment of this application, DLK (diffuse lamellar keratitis) refers to non-infectious, diffuse subcap inflammatory cell infiltration between corneal layers after laser corneal refractive surgery, and the time of occurrence is After 24 hours, it showed as fine white particle-like turbidity.

[0020] The application and its beneficial effects will be further described in detail below in conjunction with the embodiments.

[0021] This embodiment provides a low-temperature separation liquid for SMILE lens dyeing...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to an ultrasonic drug delivery device for SMILE lens dyeing low-temperature separation liquid. Wherein, the SMILE technique lens dyeing low-temperature separation liquid is kept at 0-4°C and is used for SMILE technique dyeing infiltration separation lens, including balanced salt solution and 0.005mg / ml~0.5mg / ml fluorescein sodium, balanced salt solution The ingredients include 0.29mg / ml~0.8mg / ml potassium chloride, 0.19mg / ml~0.5mg / ml calcium chloride, 0.25mg / ml~0.35mg / ml magnesium chloride, 0.3mg / ml~0.45mg / ml sodium acetate And 1.6mg / ml~2.2mg / ml sodium citrate. The low-temperature separation fluid for SMILE lens dyeing provided by this application can be dyed and infiltrated in the corneal cap (cap), the front surface of the corneal stroma lens (cap-lens layer, upper layer), and the back of the corneal stroma lens The surface (lens-posterior stroma layer, lower layer), corneal cap incision, etc., make the upper and lower surfaces of the corneal stroma lens that are difficult to distinguish visible, thereby reducing the difficulty of corneal lens separation operation, making the operation more accurate, shortening the time, and protecting the corneal cap And corneal stroma and other major structures, reducing surgical complications.

Description

technical field [0001] The invention relates to the technical field of ophthalmic refractive surgery, in particular to an ultrasonic drug delivery device for lens dyeing and low-temperature separation liquid in SMILE surgery. Background technique [0002] Femtosecond laser small incision lenticule extraction (SMILE) surgery is to use femtosecond laser to perform spatial scanning micro-blast cutting on the corneal stroma layer to make it into a lens, and then make a small incision (2-4mm) from the edge of the cornea. ) is taken out to complete a new type of refractive surgery that changes the curvature of the cornea. [0003] A large number of clinical and research data show that SMILE has excellent safety, stability and predictability, and the advantages of this "minimally invasive" corneal refractive surgery have attracted more and more attention. However, due to the limitations of the femtosecond laser, there is still a bridge-like connection between the corneal stromal l...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61F9/008A61F9/01A61F9/00A61M37/00A61N7/00
CPCA61F9/00804A61F9/0008A61M37/00A61N7/00A61F2009/00872A61M2037/0007A61M2210/0612A61M2210/005
Inventor 黎颖莉李伟力符敏李晓霞席蕾梁静陈慧琼陈丽娜赵鹏越李雪
Owner SHENZHEN HOSPITAL OF SOUTHERN MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products