Dynamic monitoring and evaluation method for pancreatic ductal adenocarcinoma

A technology for dynamic monitoring of pancreatic ductal adenocarcinoma, which is applied in the directions of biochemical equipment and methods, microbial determination/inspection, and measurement devices, and can solve the problems of insensitive detection results, unfavorable use, and long detection frequency.

Pending Publication Date: 2021-08-03
苏州崛起医疗科技有限公司
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Problems solved by technology

[0003] The existing dynamic monitoring and evaluation methods for pancreatic ductal adenocarcinoma have certain disadvantages when used. For patients after PDAC, half of the dynamic monitoring is based on imaging, the detection frequency is relatively long, the detection is not timely, and many positive The results of imaging tests of patients are not sensitive, showing false negatives, and the tumors cannot be found until the next imaging test, so the timeliness of treatment for patients is very poor, which is not conducive to people's use, and brings great harm to people's use process. Therefore, we propose a dynamic monitoring and evaluation method for pancreatic ductal adenocarcinoma

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  • Dynamic monitoring and evaluation method for pancreatic ductal adenocarcinoma

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Embodiment Construction

[0024] In order to make the technical means, creative features, goals and effects achieved by the present invention easy to understand, the present invention will be further described below in conjunction with specific embodiments.

[0025] A dynamic monitoring and evaluation method for pancreatic ductal adenocarcinoma, comprising the following steps:

[0026] S1: Select 140 patients after PDAC as test subjects, draw 10 ml of venous whole blood from each test subject before surgery, every month after surgery, until imaging progress, and use centrifugation to remove blood cells to obtain serum. If there is an interval of 4 hours between the subject and the central laboratory for centrifugation, it can be collected in a common blood collection tube containing ethylenediaminetetraacetic acid (EDTA), and then transported in ice packs;

[0027] S2: Select 1 ml of serum, divide it into 2 parts on average, and use enzyme-linked immunosorbent assay (ELISA) to detect two proteins, incl...

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Abstract

The invention discloses a dynamic monitoring and evaluation method for pancreatic ductal adenocarcinoma, which comprises the operation steps of S1, selecting 140 PDAC postoperative patients as test detection objects, extracting 10 milliliters of vein whole blood of each detection object before the operation and every month after the operation until the imaging progress, removing blood cells by adopting a centrifugal method to obtain serum, if the object is 4 hours away from the centrifugal treatment of the central laboratory, adopting a common blood collection tube containing ethylenediamine tetraacetic acid (EDTA) for collection, and then adopting an ice bag for transportation; and S2, selecting 1ml of serum, averagely dividing the serum into two parts, and respectively detecting two proteins. The dynamic monitoring and evaluation method for pancreatic ductal adenocarcinoma can more sensitively discover tumor relapse about 3 months earlier than imaging, bring early intervention to later treatment, bring the advantage of prolonging the life of a patient, make up for the defects based on imaging in the past, and bring better use prospects.

Description

technical field [0001] The invention relates to the biological field, in particular to a dynamic monitoring and evaluation method for pancreatic ductal adenocarcinoma. Background technique [0002] The dynamic monitoring and evaluation method of pancreatic ductal adenocarcinoma is a supporting method for postoperative examination of pancreatic cancer. It detects the patient's postoperative situation, and the model and parameters of the result meet the requirements of PDAD postoperative recurrence monitoring, and are consistent with the patient's The early screening examinations belong to different clinical application scenarios. With the continuous development of science and technology, people have higher and higher requirements for the manufacturing process of the dynamic monitoring and evaluation method of pancreatic ductal adenocarcinoma. [0003] The existing dynamic monitoring and evaluation methods for pancreatic ductal adenocarcinoma have certain disadvantages when us...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/574C12Q1/6858
CPCC12Q1/6858G01N33/57438G01N33/57488C12Q2523/125C12Q2531/113C12Q2537/143C12Q2535/122C12Q2537/165
Inventor 施巍炜
Owner 苏州崛起医疗科技有限公司
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