Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of new colloidal gold detection test paper and its preparation method and application

A technology for detecting test strips and colloidal gold, applied in biological tests, measuring devices, immunoassays, etc., can solve the problem of low positive coincidence rate, and achieve the effect of high positive coincidence rate, protection of protein activity, and good size uniformity

Active Publication Date: 2022-03-04
SHANGHAI BIOGERM MEDICAL TECH CO LTD
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to solve the existing novel coronavirus colloidal gold detection test paper and its preparation method and application, to solve the problem of low positive coincidence rate when the new coronavirus IgM and IgG antibody colloidal gold detection test paper detects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of new colloidal gold detection test paper and its preparation method and application
  • A kind of new colloidal gold detection test paper and its preparation method and application
  • A kind of new colloidal gold detection test paper and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0038] In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the accompanying drawings, in which several embodiments of the present invention are shown, however, the present invention can be realized in many different forms and is not limited herein The described embodiments are, on the contrary, provided so that the disclosure of the invention will be thorough.

[0039] A colloidal gold detection test paper for novel coronavirus provided by the present invention is combined below Figure 1 , Figure IIAs shown, a new coronavirus IgM and IgG antibody colloidal gold detection test paper of the present invention includes a CT box 13, a colloidal gold immunochromatography test strip 12 and a sample buffer, wherein the CT box 13 is a colloidal gold immunochromatography test paper The outer shell structure of the bar, the CT box 13 includes a sample injection hole 10 and an observation window 1...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
diameteraaaaaaaaaa
Login to View More

Abstract

The invention provides a novel coronavirus colloidal gold detection test paper and its preparation method and application. The kit of the invention has a high positive coincidence rate. The gold-labeled conjugate pad is labeled with the S protein and N protein of the new coronavirus, which can simultaneously identify the IgM antibody and IgG antibody against the new coronavirus S protein in the sample, as well as the IgM antibody and IgG antibody of the new coronavirus N protein. The pH value of the gold-labeled S protein is 7.5±0.5, and the gold-labeled S protein is evenly spread on the conjugate pad; the pH value of the gold-labeled N protein is 9.5±0.5, and the gold-labeled N protein is sprayed with a gold sprayer. On the conjugate pad; and through the differential gold labeling and treatment of S protein and N protein and the firing of colloidal gold particles using a spherical bottle and a digital jacketed magnetic stirrer, and in buffer solution 1, buffer Adding the surfactant sodium lauryl polyoxyethylene ether sulfate into solution 2 can greatly improve the detection sensitivity and improve the overall detection efficiency.

Description

technical field [0001] The invention belongs to the technical field of novel coronavirus detection, and specifically relates to a novel coronavirus colloidal gold detection test paper and its preparation method and application. Background technique [0002] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the group of coronaviruses and is the pathogen that causes the outbreak of coronavirus disease 2019. Coronaviruses are a type of zoonotic single-stranded RNA viruses that spread between animals and humans. Coronaviruses can infect mammals and birds, causing digestive tract diseases in cattle and pigs or upper respiratory tract diseases in chickens. Before the discovery of SARS-CoV-2, it was common in nature. There are six known coronaviruses that can infect humans, and four low-risk types, which mainly cause cold symptoms. They are human coronavirus 229E (HCoV-229E), Human coronavirus OC43 (HCoV-OC43), human coronavirus NL63 (HCoV-NL63), human corona...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/68G01N33/569G01N33/558G01N33/58G01N33/532G01N33/531
CPCG01N33/6854G01N33/56983G01N33/558G01N33/587G01N33/532G01N33/531G01N2333/165G01N2469/20
Inventor 魏鹏海朱兆奎梁权赵百慧
Owner SHANGHAI BIOGERM MEDICAL TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com