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Multi-station high-flux pipetting equipment

A high-throughput, multi-station technology, applied in the direction of measuring tubes/pipettes, laboratory utensils, laboratory containers, etc., can solve the deformation of supporting mechanisms, skewing of pipetting components, Liquid tip insertion failure and other problems

Active Publication Date: 2021-05-18
GUANGXI TECHCAL COLLEGE OF MACHINERY & ELECTRICITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the assembly of the pipette handle and the pipette tip is an interference fit, the pipette handle of the pipetting assembly will be subjected to very large resistance when inserting pipette tips in large quantities, and this assembly resistance will be transmitted to the supporting pipette. The support mechanism of the liquid assembly, especially when the rigidity of the support mechanism is poor, the support mechanism of the pipetting assembly will be greatly deformed, causing the pipetting assembly to be skewed, affecting the insertion effect of some pipetting tips, resulting in partial displacement Failed to insert the liquid sleeve handle and pipette tip
In addition, the loading plate of this invention has only two stations, and the box needs to be changed manually during work, which is a semi-manual operation and the work efficiency is low

Method used

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  • Multi-station high-flux pipetting equipment

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Embodiment Construction

[0048] The structure of the multi-station high-throughput pipetting device in the embodiment of the present invention is as follows: Figure 1 to Figure 20 As shown, it includes a base 02, an X-axis driving mechanism 10, a Y-axis driving mechanism 20, a Z-axis driving mechanism 30, a pipetting head 100 and two columns of pipetting instruments 200. The pipetting head 100 includes a pipetting mechanism and an insertion mechanism. Each row of pipetting instruments 200 includes a pipetting tip box 90 , a liquid sample box 95 and a test tube box 96 .

[0049] The Y-axis driving mechanism 20 includes a linear module, and the linear module of the Y-axis driving mechanism 20 is installed on the base 02 along the Y-axis direction. It includes a housing 21, a Y-axis motor 22, a synchronous belt drive, a driving block 23 and two sets of linear guide rail pairs 24. The driving block 23 is arranged above the bar-shaped housing 21 and is a hollow structure, including two side plates 231 ,...

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PUM

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Abstract

The invention discloses multi-station high-flux pipetting equipment. According to the invention, three stations are arranged on a base in a Y-axis direction; the first station comprises a first pipetting suction head containing box; the second station comprises a first liquid sample box; the third station comprises a test tube containing box; when a pipetting suction head and a pipetting sleeve handle are assembled, an inserting mechanism drives a pipetting mechanism to descend, and when the pipetting suction heads and the pipetting sleeve handles are assembled, the inserting mechanism drives a pipetting mechanism to descend; and after the sleeve handle of a pipetting assembly is inserted into the inner hole of the pipetting suction head, the inserting mechanism grabs the box body of the suction head containing box and further applies pressure to the pipetting mechanism, so the pipetting sleeve handle at the lower part of the pipetting assembly is pressed into the inner hole of the pipetting suction head. The downward press-fitting force of the pipetting assembly is balanced by pull force applied to the suction head containing box by the inserting mechanism, and the pull force is not transmitted to a bearing mechanism of the pipetting equipment to deform the bearing mechanism, so the insertion effect of the sleeve handle and the suction head is good; and since the three stations are arranged in the Y-axis direction, manual box replacement is not needed in a pipetting process, and pipetting efficiency is high.

Description

[technical field] [0001] The invention relates to liquid pipetting equipment, in particular to a multi-station high-throughput liquid pipetting equipment. [Background technique] [0002] Pipetting is an important operation in the fields of biology and medicine, and one of the basic operations of various research experiments. Pipette guns are mostly used in the work involving pipetting and titration. Most of the liquid taking and discharging processes of these instruments rely on manual operations, which are prone to problems such as missing liquids and forgetting to rinse. [0003] Automatic liquid pipetting equipment is an automatic liquid processing instrument that can replace traditional liquid pipetting tools, and can automatically complete high-precision liquid processing tasks such as gradient dilution, pipetting, and merging liquids, and can be used in conjunction with detection instruments to achieve the target Efficient and accurate detection of substances. The fu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/02
CPCB01L3/0227B01L3/0234B01L3/0293
Inventor 黄增廖剑斌苏茜李华川余小榕邓桂丹
Owner GUANGXI TECHCAL COLLEGE OF MACHINERY & ELECTRICITY
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