Method for researching alcoholic bone remodeling based on marrow fluid metabonomics

Abstract

The invention relates to the technical field of bone remodeling, in particular to a method for researching alcoholic bone remodeling based on marrow fluid metabonomics. The bone remodeling steps comprise: Step 1, performing CT (Computed Tomography) on a leg of a patient suffering from a malignant tumor so as to determine the range of the tumor attached to the bone; Step 2, enabling the patient to lie flat on a sickbed, then splitting the tumor part of the leg of the patient, and next cutting off the bone with the tumor part through cutting-off equipment; and Step 3, drilling positioning holes in outer sides of two sections of the cut bone through hole drilling equipment. By using the method, the cut-off bone is subjected to soaking tumor removing treatment, and is then reset again; through cooperation with autonomous metabolism of marrow fluid and auxiliary supporting extrusion of a positioning mechanism, the bone remodeling effect is guaranteed, and the bone remodeling period is also shortened; an additional supporting mechanism does not need to be additionally added to the remodeling part, so that a repulsion phenomenon is avoided; the self repair of bone remodeling is well realized; and the reliability of bone remodeling is greatly improved.

Description

technical field [0001] The invention relates to the technical field of bone remodeling, in particular to a method for studying alcoholic bone remodeling based on bone marrow fluid metabolomics. Background technique [0002] Bone remodeling refers to the physiological behavior in which the shape and density of bone tissue change with changes in the biomechanical environment. Qualitatively speaking, in areas with higher loads, bone mass and density increase, while in areas with lower loads, bone mass and density increase. The quality and density of bone tissue decreases, and the characteristic of bone tissue that becomes stronger when used and becomes weaker when it is used reflects its adaptability to the biomechanical environment, so that it can achieve the maximum bearing capacity with the least amount of bone in a specific mechanical environment. ability, when the bone is in an unfavorable external force environment, its shape and density will undergo abnormal changes, suc...

AI Technical Summary

Problems solved by technology

[0002] Bone remodeling refers to the physiological behavior in which the shape and density of bone tissue change with changes in the biomechanical environment. Qualitatively speaking, in areas with higher loads, bone mass and density increase, while in areas with lower loads, bone mass and density increase. The quality and density of bone tissue decreases, and the characteristic of bone tissue that becomes stronger when used and becomes weaker when it is used reflects its adaptability to the biomechanical environment, so that it can achieve the maximum bearing capacity with the least amount of bone in a specific mechanical environment. ability, when the bone is in an unfavorable external force environment, its shape and density will undergo abnormal changes, such as osteoporosis caused by a weightless environment, stress shielding caused by implants, etc. With the continuous development of society, Some methods of bone remodeling began to appear continuously, but the traditional partial resection method has poor effect on bone remodeling and takes a long period of time. It needs to add auxiliary support structures in the bone, which is not conducive to the self-repair of the bone, and is prone to infection and disease. The phenomenon of rejection, the reliability is low, therefore, a method based on bone marrow fluid metabolomics to study alcoholic bone remodeling is proposed to solve the above problems