A traditional Chinese medicine composition for treating ischemic cerebrovascular disease and its application

Abstract

The invention discloses a traditional Chinese medicine composition for promoting blood circulation and application thereof, belonging to the field of medicine. The object of the present invention is to provide an effective medicine for treating cerebral ischemia injury. The invention provides a traditional Chinese medicine composition for promoting blood circulation. The composition is composed of the following ingredients: buffalo horn, pangosaurus, leech, earthworm, notoginseng, rehmannia glutinosa, angelica, salvia miltiorrhiza, summerless, ashen and dried lacquer. Crushed and sieved, decocted to prepare extract, dried and other processes to obtain tablets. The composition for invigorating blood circulation provided by the present invention improves the abnormal neurological behavior of animals caused by cerebral ischemia, reduces the area of ​​cerebral infarction in rats with cerebral ischemia, improves the loss of neurons in the ischemic penumbra area of ​​the cerebral cortex, and improves the situation of cerebral edema. Reduce the penetration of EB in the blood-brain barrier, improve the shrinkage of neurons, the reduction of the number of synapses and the destruction of capillary basement membrane, etc., and protect the brain tissue from cerebral ischemia. It can be used as a specific drug for the treatment of ischemic cerebrovascular diseases. .

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for promoting blood circulation and its application. Background technique [0002] Ischemic cerebrovascular diseases (ICVD) refer to the necrosis or softening of local brain tissue that occurs when the blood supply is interrupted or insufficient, and the disease usually manifests as certain neurological deficit symptoms. ICVD is a common disease with high mortality and high disability rate, and it mostly occurs in middle-aged and elderly people. Since the pathogenesis of the disease is not yet fully understood, its treatment drugs are relatively scarce. The disease not only reduces the living standard of middle-aged and elderly people, but also increases the economic burden of society and family to a certain extent. [0003] In recent years, some new achievements have been made in the research on the treatment of cerebral ischemic i...

AI Technical Summary

Problems solved by technology

However, in the acute stage, thrombolysis and symptomatic treatment are mainly used, and thrombolytic therapy is limited by time (i.e., thrombolytic therapy is used within 6 hours of onset), so it can be seen that the development of drugs that can restore the blood supply to cerebral ischemic areas as soon as possible is of great significance. Significance

Ischemic cerebrovascular disease has the characteristics of high morbidity, high mortality and high disability rate, which seriously endanger human health. The main treatment methods are ultra-early thrombolysis, symptomatic and supportive therapy, and there is still a lack of specific drugs for this disease.

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