A physical simulation model device of hemodynamics in vitro of arteriovenous fistula

A technology of arteriovenous fistula and flow mechanics, applied in the field of simulation, can solve problems such as inconsistent results and long experiment period

Active Publication Date: 2022-03-15
FUJIAN UNIV OF TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] According to the literature at home and abroad, researchers at home and abroad are based on actual patients when conducting arteriovenous fistula research, but there is specificity among patients, and the data collected in the same period of internal fistula in different patients may cause inconsistent results; During the experiment, due to the periodicity of fistula establishment to maturity, the experiment period is long.

Method used

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  • A physical simulation model device of hemodynamics in vitro of arteriovenous fistula
  • A physical simulation model device of hemodynamics in vitro of arteriovenous fistula
  • A physical simulation model device of hemodynamics in vitro of arteriovenous fistula

Examples

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Effect test

Embodiment 1

[0058] In this example, the simulated blood is a mixed glycerol-water (38%-62% by volume) liquid. At 28°C, the viscosity is 3.2×10 -6 m 2 / s, and the density is 1090 kg / m 3 .

[0059] The overall structure of the model in this example is as follows figure 1 As shown, the model contains a reservoir bucket 1 (simulating heart vessel 1) to simulate the heart as the source of inflow and outflow of blood, and a pump 2 transports the blood to the funnels 3 and 4 (radial artery blood pressure simulation vessel 3, head Venous blood pressure simulation container 4), according to the blood pressure of the patient's B-ultrasound radial artery and cephalic vein, the systolic blood pressure is converted from the unit of mmHg and bar, and the funnels 3 and 4 are placed at different heights h1 and h2, respectively. The liquid level sensor will drive the corresponding pump to act when the liquid is lower than a certain value. When the liquid level reaches this value, the suction pump wil...

Embodiment 2

[0061] Further, in Example 1, different mixing ratios were used to make silicone models with different elasticity, the size of the skin was 15*15*8mm, and the universal testing machine was used to measure to select the skin that is closest to the skin parameters reported in the literature. mold. The cross-sectional view of the fistula end-to-side coupling is shown in figure 2 As shown in the figure, two main pipes (92 - radial artery simulation input tube; 93 - capillary simulation input blood vessel) flow to the radial artery inlet and capillary inlet of the fistula simulator 9 to simulate the skin, respectively. In the model of the fistula simulator 9 , there is a cephalic vein simulation output tube 93 vein outlet at the simulated skin, the cephalic vein 94 and the radial artery 92 form an arteriovenous fistula 95, the blood vessels are placed in the elastic silicone of the simulated skin 91, and the whole artificial skin is placed in a 20*20* In the 20mm airtight iron bo...

Embodiment 3

[0063] Further, in the embodiment 2, the human vascular model setting process is as follows: image 3 As shown in the figure, before the model starts to work, place the two water pipes at a certain height. This height is obtained by unit conversion according to the systolic blood pressure of the radial artery and cephalic vein of the patient before the fistula is established. The next two are to check the water storage bucket 1 Whether the water in the model is enough to fill the water pipes in this model, whether the liquid level sensors 3 and 4 will alarm and trigger the pump to work, and then set the respective conduction time of the two diverter valves 5 and 6, which is measured by the The devices 7 and 8 measure the pressure and flow rate, and observe whether the waveform of the blood pressure is close to the normal waveform. If yes, go to the next step; otherwise, adjust the on-time until the Figure 4 up to the result.

[0064] Then set the systolic and diastolic blood...

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Abstract

The present invention proposes an arteriovenous fistula external hemodynamics physical simulation model device, the simulated blood circuit includes a simulated heart container, a radial artery blood pressure simulation container, a cephalic vein blood pressure simulation container and a fistula simulator equipped with a measuring device; The installation height of the arterial blood pressure simulation container and the cephalic vein blood pressure simulation container is higher than that of the simulated heart container; the fistula simulator is equipped with a fistula simulation cavity surrounded by elastic simulated skin; the input end of the fistula simulation cavity is respectively connected to the radial artery blood pressure simulation container , the cephalic vein blood pressure simulation container, and the output port is connected to the simulated heart container; when the simulation is performed, the fistula simulation cavity reaches the required deformation, and the simulated blood in the radial artery blood pressure simulation container and the cephalic vein blood pressure simulation container flows back through the fistula simulation cavity To simulate the heart container, the measuring device of the fistula simulator measures the pressure and flow velocity of the blood flowing through the input end and the output end; the invention can establish a set of stable blood vessel models with controllable stenosis.

Description

technical field [0001] The invention relates to the technical field of simulation, in particular to an external hemodynamic physical simulation model device of an arteriovenous fistula. Background technique [0002] With the development of China's economy, the acceleration of industrialization, urbanization, and behavioral and demographic changes have led to an increase in the morbidity and related mortality of chronic non-communicable diseases, of which chronic kidney disease (CKD) is the most prominent, and hemodialysis is the most important for patients with kidney disease. Autologous arteriovenous fistula (AVF) should be the first choice for long-term vascular access. [0003] According to domestic and foreign literatures, domestic and foreign researchers are all based on actual patients when they conduct arteriovenous fistula research, but there is specificity between patients. During the experiment, there is a problem of long experiment period due to the periodicity o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G09B23/28A61B5/02
CPCG09B23/28A61B5/02028A61B5/02035
Inventor 罗堪黄炳法李建兴马莹黄靖陈炜赖智晨杨睿宁沈亮刘肖蔡聪
Owner FUJIAN UNIV OF TECH
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