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Breast cancer sentinel node biopsy method

A technology of sentinel lymph node and lymph node, which is applied in the field of lymph node biopsy, can solve the problems of long freezing time of sentinel lymph node biopsy results of breast cancer, etc., and achieve the effect of shortening the waiting time for anesthesia, speeding up the turnover and utilization, and reducing the probability of infection

Inactive Publication Date: 2020-11-03
云南省肿瘤医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the existing technical problem of waiting too long for the freezing result of sentinel lymph node biopsy of breast cancer, the purpose of the present invention is to provide a method of sentinel lymph node biopsy of breast cancer, which shortens the time to 3-5 minutes and can perform axillary lymph node dissection in time , to effectively shorten the operation time requiring axillary dissection, specifically including the following steps:

Method used

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Embodiment Construction

[0013] The present invention will be described in further detail below in conjunction with specific embodiments, but the protection scope of the present invention is not limited to the content described.

[0014] A breast cancer sentinel lymph node biopsy method specifically comprises the following steps:

[0015] (1) Specimen collection: acquisition of sentinel lymph nodes, preoperative sentinel lymph tracing (the most commonly used SLNB tracing method is dye (mainly methylene blue, 62.73%), followed by nanocarbon (16.36%) and nuclide combination Blue dye (14.55%), fluorescence (5.45%) and nuclide (0.91%) were used relatively less); nuclide combined with blue dye double staining method was the gold standard. At the beginning of the operation, 2ml of the tracer was injected subcutaneously along the 3, 6, 9, 12 points of the areola or around the tumor. After 5-10 minutes, after routine disinfection during the operation and the laying of sterile towels, the breast-conserving sur...

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PUM

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Abstract

The invention discloses a breast cancer sentinel node biopsy method, and belongs to the technical field of lymph node biopsy According to the method disclosed by the invention, a rapid field assessment (ROSE) technology is applied to breast cancer sentinel lymph node biopsy, so that in-vitro specimens in an operation can be timely subjected to field slide preparation and dyeing in an operation room, and an operation doctor can rapidly make an assessment within only 3-5 minutes; specimens required for slide preparation and dyeing in the whole process do not affect further intraoperative freezing and postoperative paraffin, results are repeatedly compared with intraoperative freezing and postoperative paraffin results through early-stage experiments, pasteurization and HE staining result verification is performed on the intraoperative lymphocyte printing sheet after the operation; the mutual coincidence rate of cytological and histological diagnosis results can reach 100%.

Description

technical field [0001] The invention relates to a breast cancer sentinel lymph node biopsy method, which belongs to the technical field of lymph node biopsy. Background technique [0002] Sentinel lymph node (Sentinel lymph node, SLN) is the first lymph node to receive lymphatic drainage in the tumor area and tumor metastasis. If this lymph node does not metastasize, the probability of other lymph nodes metastasizing is very small, estimated to be less than 5% or less . Predict whether the axillary lymph nodes have metastasis by sentinel lymph node biopsy, so as to avoid surgical dissection of axillary lymph nodes without metastasis, reduce postoperative complications such as lymphatic reflux edema and pain in the affected limbs, simplify surgical procedures, and significantly improve breast cancer Patient quality of life. [0003] The existing steps of breast cancer sentinel lymph node biopsy include: preoperative sentinel lymph tracing (the most commonly used SLNB tracin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/28G01N1/30G01N1/36G01N1/42A61B10/02
CPCA61B10/0233G01N1/28G01N1/30G01N1/36G01N1/42
Inventor 汤琦周绍强晋萍李惠
Owner 云南省肿瘤医院
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