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A traditional Chinese medicine for treating infantile intrahepatic cholestatic liver disease based on liver collateral disease theory

A technique for cholestasis and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine for treating infantile intrahepatic cholestatic liver disease

Active Publication Date: 2021-09-14
BEIJING CHILDRENS HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are no reports of drugs for the treatment of infant liver disease based on the theory of liver collateral disease

Method used

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  • A traditional Chinese medicine for treating infantile intrahepatic cholestatic liver disease based on liver collateral disease theory
  • A traditional Chinese medicine for treating infantile intrahepatic cholestatic liver disease based on liver collateral disease theory
  • A traditional Chinese medicine for treating infantile intrahepatic cholestatic liver disease based on liver collateral disease theory

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Experimental program
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Effect test

Embodiment 1

[0020] A traditional Chinese medicine for treating infantile intrahepatic cholestatic liver disease based on the theory of liver-collateral disease. It is made of the following raw materials: capillary root 12g, Bupleurum 9g, Citrus aurantium 9g, Rhizoma Chuanxiong 9g, raw malt 9g, peach kernel 3g, red Flower 3g, Radix Paeoniae Rubra 12g, Achyranthes bidentata 9g, Eupatorium 3g, Angelica 6g, Rehmannia 6g, Atractylodes macrocephala 9g, Curcuma 9g, the traditional Chinese medicine was made into a decoction for oral administration.

Embodiment 2

[0022] A traditional Chinese medicine for treating infant intrahepatic cholestatic liver disease based on the theory of liver-collateral disease. It is made of the following raw materials: 10g capillary, 7g Bupleurum, 7g Citrus aurantium, 8g Chuanxiong, 8g raw malt, 4g peach kernel, Flower 4g, Radix Paeoniae Rubra 10g, Achyranthes bidentata 8g, Eupatorium 4g, Angelica 7g, Shengdi 8g, Atractylodes macrocephala 10g, Curcuma 8g, the traditional Chinese medicine is made into oral liquid for oral administration.

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Abstract

The invention relates to a traditional Chinese medicine for treating infant intrahepatic cholestatic liver disease based on the theory of liver-collateral disease. The prescription uses peach kernel, safflower, red peony root and eupatorium as monarch drugs, and is mainly used to promote blood circulation and remove blood stasis, and remove liver-collateral stasis; The official medicines are Bupleurum, Curcuma, Chuanxiong, Citrus aurantium to soothe the liver and promote qi, soothe the stagnation of qi in the liver and collaterals, adjuvant with angelica, raw land to nourish the blood and nourish the liver, raw malt, Atractylodes macrocephala, and Yin Chen to soothe the liver, promote stomach qi, and strengthen the spleen Dispelling dampness and harmonizing the stomach, combined with Achyranthes bidentata to promote blood circulation and nourish the liver and collaterals. The traditional Chinese medicine of the present invention significantly improves laboratory indicators such as liver function and clinical indicators such as cholestasis and coagulation function, and the total clinical effective rate of treating infant intrahepatic cholestatic liver disease is better than that of existing western medicines such as ursodeoxycholic acid. And it has the advantages of good compliance, less dosage, quick effect and less side effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for treating infant intrahepatic cholestasis liver disease based on liver collateral disease theory, belonging to the field of traditional Chinese medicine application. Background technique [0002] Infant cholestatic liver disease is a common disease in infant liver disease, and has become the first hospitalization cause of liver disease in children in China. If the cholestasis persists and is not relieved, it can accelerate liver cell damage and develop into liver fibrosis and cirrhosis as the disease progresses, endangering the health and life of the children. Cholestasis is generally divided into intrahepatic cholestasis and extrahepatic cholestasis. The causes of intrahepatic cholestasis are complex and related to premature birth, infection, genetic metabolism and other factors. Western medicine mainly focuses on symptomatic treatment, and there is no specific treatment. Liver transplantati...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/08A61P1/16
CPCA61K9/0095A61K36/21A61K36/232A61K36/233A61K36/236A61K36/282A61K36/284A61K36/286A61K36/53A61K36/65A61K36/71A61K36/736A61K36/752A61K36/804A61K36/8998A61K36/9066A61P1/16A61K2300/00
Inventor 张艳菊何强王晓玲
Owner BEIJING CHILDRENS HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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