Preparation process of oseltamivir phosphate capsules
A technology for the preparation of oseltamivir phosphate and capsules, which is applied in the directions of capsule delivery, medical preparations without active ingredients, and medical preparations containing active ingredients, etc. It can prevent the flow of A and B, the effect is excellent, and the treatment is good.
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[0015] In order to deepen the understanding of the present invention, the present invention will be further described below in conjunction with examples, which are only used to explain the present invention and do not constitute a limitation to the protection scope of the present invention.
[0016] This example provides a preparation process for oseltamivir phosphate capsules, which includes the following steps: Step 1: Screening: Weigh API, pregelatinized starch, povidone (K30) and cross-linked carboxymethyl cellulose Sodium plain, then sieve separately to reach the specified mesh number;
[0017] Step 2: Mixing: first add the raw material API into the wet granulator, then add the rest of the materials, turn on the stirring paddle, and mix;
[0018] Step 3: Add wetting agent: turn on the stirring and cutting knife, and add wetting agent to the material;
[0019] Step 4: Granulation: Turn on the stirring and cutting knife for granulation;
[0020] Step 5: Drying: Add the we...
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