Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition for preventing and treating diarrhea of newborn piglets through sow medication and application thereof

A newborn piglet and composition technology, which is applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems affecting the newborn piglet's disease defense ability and later growth, and achieve the anti-tumor immune system function of the body , Strong immune function, improve the effect of the body's immune system

Active Publication Date: 2020-08-28
浙江康嘉基因技术有限公司
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Since the health of the sow seriously affects the defense ability of newborn piglets against diseases and their later growth,

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition for preventing and treating diarrhea of newborn piglets through sow medication and application thereof
  • Traditional Chinese medicine composition for preventing and treating diarrhea of newborn piglets through sow medication and application thereof
  • Traditional Chinese medicine composition for preventing and treating diarrhea of newborn piglets through sow medication and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The preparation of embodiment 1 composition 1

[0026] According to the proportion of the prescription, weigh 10-20 parts of Bupleurum bupleurum, 10-20 parts of honeysuckle, 8-15 parts of astragalus polysaccharide, 10-20 parts of Houttuynia cordata, and 10-20 parts of forsythia. After cleaning and removing impurities, add 8- Purified water with 10 times the weight of medicinal materials, decocted 2-3 times, 1 hour each time, filtered and combined the filtrate, concentrated into a thick paste with a relative density of 1.32-1.35 (50-55°C) by conventional methods, and added appropriate amount of auxiliary materials, Such as soluble starch, sucrose powder, etc., and dry to obtain powder.

Embodiment 2

[0027] The preparation of embodiment 2 composition 2

[0028] According to the proportion of the prescription, weigh 5-15 parts of Bupleurum, 5-15 parts of honeysuckle, 5-15 parts of astragalus polysaccharide, 5-15 parts of Houttuynia cordata, 5-15 parts of forsythia, after cleaning and removing impurities, add 8- Purified water 10 times the weight of medicinal materials, decocted 2-3 times, 1 hour each time, filtered and combined the filtrate. Add 2 times the volume of filtrate water for injection (V:V=1:2), filter through a 0.45μm organic filter to obtain the filtrate; then sterilize the filtrate at 121°C and 0.15Mpa for 20min to obtain the aqueous solution.

[0029] Under sterile conditions, porcine IFN-γ is added to the aqueous preparation at a weight ratio of 20-200 μg / g to obtain composition 2.

Embodiment 3

[0030] Embodiment 3 composition clinical trial research

[0031] 3.1 Test traditional Chinese medicine composition:

[0032]

[0033]

[0034] 3.2 Test location: A large-scale pig farm in Zhejiang, with 1,000 sows in stock. Before the test, piglets in the farrowing room of the pig farm had unexplained diarrhea. Conventional treatment (such as antibiotic therapy and oral rehydration salts, etc.) had no obvious Effect.

[0035]3.3 Test animals: select 83 newborn sows with similar parity, body weight, age and delivery period, and divide them into 8 groups at random, which are respectively Chinese medicine composition of the present invention and a control group. The selected sows had the same immunization procedures, and the feeding and management conditions were the same during pregnancy and postpartum, and they were all kept in a single stall.

[0036] 3.4 Test plan

[0037] 3.4.1 Treatment plan: Composition 1 is administered orally by mixed feeding, administered twice...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating diarrhea of newborn piglets through sows. The composition comprises a composition 1 and a composition 2,wherein the composition 1 is prepared from the following components in parts by weight: 10-20 parts of radix bupleuri, 10-20 parts of flos lonicerae, 8-15 parts of radix astragali polysaccharide, 10-20 parts of herba houttuyniae and 10-20 parts of fructus forsythia; the composition 2 is an injection water agent and is prepared from the following components in parts by weight: 5-15 parts of radix bupleuri, 5-15 parts of flos lonicerae, 5-15 parts of radix astragali polysaccharide, 5-15 parts of herba houttuyniae and 5-15 parts of fructus forsythia; the composition 2 also contains swine IFN-gamma; and the content of the swine IFN-gamma is 20-200 [mu]g/g. The composition 1 and the composition 2 are combined for use, so that the health condition and immunity of the sows are greatly improved, and the innate diarrhea defense capacity of piglets is greatly improved.

Description

technical field [0001] The invention relates to a veterinary medicine, in particular to a traditional Chinese medicine composition for preventing and treating diarrhea of ​​newborn piglets by taking medicine for sows and an application thereof. Background technique [0002] The pig industry occupies a dominant position in the development of animal husbandry in my country, and the health of pigs and the survival rate of newborn piglets have become the key factors restricting the development of the industry. Since 2010, large-scale pig farms in my country have experienced a pandemic trend of newborn piglet diarrhea. The disease has high morbidity and mortality. In severe large-scale pig farms, piglets with severe disease have diarrhea in the whole litter of newborn piglets, and the mortality rate Up to more than 80%, resulting in heavy losses in pig farms, it has become a major problem affecting today's pig industry. The main impact of the disease is reflected in higher mortal...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/78A61K38/21A61P1/12A61K31/715
CPCA61K36/233A61K36/355A61K31/715A61K36/78A61K36/634A61K38/217A61P1/12A61K2300/00
Inventor 查银河舒建洪李复煌杨芳黄磊盛敏成
Owner 浙江康嘉基因技术有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com