Prophylactic and/or therapeutic agent for pneumococcal infection
A technology of Streptococcus pneumoniae and therapeutic agent, which is applied in the field of prevention and/or therapeutic agent of Streptococcus pneumoniae infection, and can solve problems such as inoculation status discomfort and the like
Active Publication Date: 2020-08-14
NUTRI CO LTD
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Problems solved by technology
[0004] However, the existence of Streptococcus pneumoniae resistant to antimicrobial drugs has been confirmed, and there have been reports of inoculation discomfort with vaccines, and new countermeasures are expected due to such problems.
Method used
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Embodiment 1
[0071] [Example 1] Effect of administering heat-sterilized lactic acid bacteria Enterococcus faecalis (E.faecalis) to Streptococcus pneumoniae-infected mice
[0072] Streptococcus pneumoniae-infected mice were prepared, and heat-sterilized lactic acid bacteria Enterococcus faecalis (E. faecalis) were orally administered to study the preventive and therapeutic effects.
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Abstract
Provided is a novel prophylactic and / or therapeutic agent for a pneumococcal infection. It is found that bacteria belonging to the genus enterococcus can prevent and / or treat a pneumococcal infection.Provided is a prophylactic and / or therapeutic agent for a pneumococcal infection, the agent containing bacteria belonging to the genus enterococcus. Provided is a prophylactic and / or therapeutic medicine for a pneumococcal infection, the medicine containing bacteria belonging to the genus enterococcus. Provided is a prophylactic and / or therapeutic food for a pneumococcal infection, the food containing bacteria belonging to the genus enterococcus.
Description
technical field [0001] The present invention relates to prophylactic and / or therapeutic agents for Streptococcus pneumoniae infection. Background technique [0002] Streptococcus pneumoniae is a gram-positive diplococcus known as a resident bacterium of the upper trachea. It is a major respiratory pathogen. [0003] According to the report of the National Institute of Infectious Diseases (Japan), Streptococcus pneumoniae is the pathogenic microorganism with the highest frequency in community-acquired pneumonia (CAP) (non-patent literature 1), and the correlation between CAP and medical care and nursing has been reported in this hospital In the prospective study of pneumonia (NHCAP), the frequencies of Streptococcus pneumoniae were 34.8% and 33.9%, respectively, which were the most (Non-Patent Document 2). Compared with patients who did not have it at all, it climbed to 12.1 times (95% confidence interval [CI] 4.1-36.2) (non-patent document 3). From October 1, 2010 (Heisei...
Claims
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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/744A23L33/135A61P11/00A61P31/04
CPCA61K35/744A61P11/00A23L33/135A61P31/04A23V2002/00A23V2200/324
Inventor 川口晋加藤美穗
Owner NUTRI CO LTD
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