Intestinal flora microorganisms for evaluating sexual precocity of children

Abstract

The invention provides intestinal flora microorganisms for evaluating sexual precocity of children. The method comprises the following steps of: comparing intestinal flora data of an object with intestinal flora data of healthy children; and mainly analyzing the relative abundance of streptococcus, neisseria, haemophilus, porphyromonsginglivlis, megacoccus, phascolarctobacterium, clostridium, coprococcus and prevotella, wherein the relative abundance of the streptococcus, the neisseria, the haemophilus and the porphyromonsginglivlis is reduced, and the relative abundance of the megacoccus, thephascolarctobacterium and the clostridium is increased. Therefore, the streptococcus, the neisseria, the haemophilus, the porphyromonsginglivlis, the megacoccus, the phascolarctobacterium and the clostridium have higher specificity and sensitivity. Therefore, the streptococcus, the neisseria, the haemophilus, the porphyromonsginglivlis, the megacoccus, the phascolarctobacteriumand the clostridiumhave higher specificity and sensitivity. In the process of evaluating the sexual precocity of children, detection and research results are compared to evaluate the level change of intestinal flora microorganisms of children, and whether the risk of the sexual precocity exists or not is judged according to the level change of the intestinal flora microorganisms.

Description

technical field [0001] The present application relates to the field of biomedical technology, in particular to an intestinal flora microorganism used for evaluating children's precocious puberty. Background technique [0002] In recent years, with the improvement of the living standards of Chinese residents, changes in diet structure and environmental factors, more and more children have secondary sexual characteristics that do not match their real age, and precocious puberty has become one of the most common endocrine diseases in children. And the frequency of the disease is increasing year by year, which has attracted the attention of pediatric experts worldwide. At present, it is generally believed in our country that precocious puberty can be defined as the development of secondary sexual characteristics for girls before the age of 8 and boys before the age of 9, and most of them are girls. According to the survey data released by the China Association for Health Promot...

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Problems solved by technology

[0004] The relationship between the microbial community in the human gut and the host is recorded as close, and intestinal flora dysbiosis is closely related to a variety of clinical diseases; the role of intestinal flora in the process of precocious puberty in children is not clear, and it is possible to find ways to use it to treat children. Microbial markers for the evaluation of precocious puberty are of great significance for exploring the mechanism of gut flora in the process of precocious puberty in children; and currently evaluating the occurrence of precocious puberty in children requires, in addition to the appearance of secondary sexual characteristics visible to the naked eye, also Taking venous blood for testing of sex hormone indicators, children are very afraid and disgusted with the tingling sensation when drawing blood, and their cooperation is low

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