A personalized lower limb long bone segment substitute and its preparation method

Abstract

The invention discloses a personalized lower limb long bone segment substitute and a preparation method thereof. The personalized lower limb long bone segment substitute comprises a long bone segmentpart and a fixed wing, the long bone segment part is of a hollow structure, the shape of the long bone segment part is matched with the shape of a defective long bone segment of a human body, and thelong bone segment part comprises a supporting body designed and obtained through a topological optimization method under various gait conditions and a porous filling part with a gradient porous structure. Wherein the contour shape of the fixed wing is obtained through a topological optimization design method under various gait conditions; according to the preparation method, an additive manufacturing technology or a machining technology is adopted, and integrated manufacturing or separated manufacturing is combined for use; the strength of the substitute is guaranteed while the weight of the substitute is reduced, the stress conduction capacity of the substitute is improved through the gradient porous structure, and the service life of the substitute in a human body is prolonged.

Description

technical field [0001] The invention belongs to the technical field of personalized bone substitutes, and in particular relates to a personalized lower limb long bone segment substitute and a preparation method thereof. Background technique [0002] Long bone tumors seriously endanger the lives of patients. The usual treatment is to resect the tumor segment of the long bone, and use artificial materials to make a prosthesis and implant it into the human body to reconstruct the bone at the resected part and restore the load-bearing and motor functions of the lower limbs. Since bone morphology and tumor location vary from patient to patient, individualized reconstruction is required when reconstructing the resected bone segment. Traditionally, there are two methods of personalized reconstruction of long bone segments of the lower limbs. One is to manufacture modular long bone segment replacement prostheses by machining methods. When using them, different parts can be combined ...

AI Technical Summary

Problems solved by technology

[0003] The current long bone segment substitutes produced by 3D printing have the following problems. The design of the substitute only considers how to reconstruct the shape of the resected bone segment, and lacks consideration of the mechanical environment when the substitute is used in the human body, which may cause post-implantation problems. Fatigue fracture of the prosthesis caused by long-term cyclic loading, loose fixation between the prosthesis and the bone, or long-term loosening of the prosthesis caused by bone loss around the prosthesis seriously affect the service life of the prosthesis in the human body.

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