An image correction method for high-resolution optical coherence confocal microscopy

Abstract

The invention discloses an image correction method for high-resolution optical coherence confocal microscopy, which can improve the curvature artifacts caused by the position shift of the coherence gate due to the use of high numerical aperture lenses in the optical coherence confocal endoscopy system, and The problem of fuzzy deformation at the edge of the field of view; this technical solution analyzes and restores the phase information of the reference surface, establishes a calibration phase mapping table, and maps this table to the original image, thereby correcting the curvature of the coherence gate. This phase information can be directly used for OCM The coherence processing of the image, as well as any order of system dispersion, can be corrected and eliminated by calculation, so as to improve the imaging performance without changing the optical path structure of the system. This method is used for optical coherence confocal endoscopic microscopy systems and In a similar imaging system, the miniaturization of the probe and the balance of imaging quality are taken into account, making it a fast, non-staining, high-sensitivity and specific medical diagnostic tool.

Description

technical field [0001] The invention relates to an image correction method, in particular to an image correction method for high-resolution optical coherent confocal microscopy. Background technique [0002] In the field of medical imaging, OCT (Optical Coherence Tomography) scanning, as a novel optical imaging technology, can help medical staff observe the structure and shape of tissues and find tiny lesions. Based on the principle of light interference, it uses infrared light as the light source, can penetrate a certain depth of the scanning medium, and recover the detection signal into a longitudinal cross-sectional view of the tissue through calculation. It has the advantages of high resolution, non-contact, and no marking. The judgment method of in vivo pathology reflects important information such as the internal structure and scattering coefficient of biological tissues. In recent years, it has become a research hotspot to combine OCT technology with other imaging te...

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide an image correction method for high-resolution optical coherence confocal microscopy, which aims to solve the curvature artifacts caused by the position shift of the coherence gate due to the use of high numerical aperture lenses in the optical coherence confocal endoscopy system. Shadow, and the problem of blurred deformation at the edge of the field of view

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