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Medical composition for preventing or treating sexual dysfunction and use of medical composition

A composition and sexual function technology, applied in the field of medicine, can solve the problems of not disclosing the medical use of sexual dysfunction, not disclosing the pharmaceutical composition of yohimbine and ginkgolide, limiting the scope of application of yohimbine, etc., reaching clinical Medication safety and the effect of reducing the incidence of side effects

Inactive Publication Date: 2020-01-17
CHENGDU BAIYU PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Long-term use of yohimbine may lead to myocardial infarction, and patients with liver damage and heart disease should not use it
This also limits the scope of application of yohimbe to a certain extent
[0007] After searching, the prior art does not disclose the pharmaceutical composition with these two types of compounds, yohimbine and ginkgolide as active ingredients, nor disclose its medical use for treating and / or preventing sexual dysfunction

Method used

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  • Medical composition for preventing or treating sexual dysfunction and use of medical composition
  • Medical composition for preventing or treating sexual dysfunction and use of medical composition
  • Medical composition for preventing or treating sexual dysfunction and use of medical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0141] Embodiment 1 Ginkgolide Yohimbine Tablet

[0142] Yohimbine 0.135g, ginkgolide 200g, supplemented with conventional pharmaceutical excipients for tablets, prepared by conventional tablet preparation methods.

Embodiment 2

[0143] Embodiment 2 ginkgolide yohimbine capsules

[0144] Yohimbine 0.27g, ginkgolide 100g, supplemented with conventional pharmaceutical excipients for capsules, prepared by a conventional preparation method for capsules.

Embodiment 3

[0145] Embodiment 3 ginkgolide yohimbe gum dripping pills

[0146] Yohimbine 5.4g, ginkgolide 10g, supplemented with conventional pharmaceutical excipients for dropping pills, prepared by a conventional preparation method for dropping pills.

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Abstract

The invention discloses a medical composition containing ginkgolides and Yohimbine hydrochloride in effective quantity, and use of the medical composition containing ginkgolides and Yohimbine hydrochloride in effective quantity to preparation of medical compositions for preventing and / or treating sexual dysfunction, and belongs to the field of pharmaceuticals. Specifically, for each preparation unit of the medical composition disclosed by the invention, the effective quantity of the Yohimbine hydrochloride is 0.135 mg-16.2 mg and the effective quantity of the ginkgolides is 10 mg-600 mg. According to the medical composition disclosed by the invention, the ginkgolides and Yohimbine are in combined usage or jointed usage to achieve synergistic effects, are high in total effective rate, highin speed of taking effect, long in action time, low in side effect occurrence rate and good in treatment effects on male erectile dysfunction such as vascular erectile dysfunction, senile erectile dysfunction and neurogenic erectile dysfunction when being used for preventing and / or treating the sexual dysfunction.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition containing ginkgolide and yohimbine, and its use in preparing a pharmaceutical composition for preventing and / or treating sexual dysfunction. Background technique [0002] Erectile dysfunction (erectile dysfunction, ED) is a male sexual dysfunction, refers to the persistent inability of the penis to achieve and (or) maintain a sufficient erection for satisfactory sexual life (coitus). ED is a common and frequently-occurring disease in andrology. According to statistics, 52% of men aged 40 to 70 have different degrees of ED. According to the statistics of WHO, the global ED patients have reached 150 million people, and the global incidence rate is 4% (Duan Xueguang. An overview of tadalafil treatment of ED. "Chinese Journal of Andrology". 2013-19(4): 380-383 ). The occurrence of ED not only affects the quality of life of patients, but also brings...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/475A61K31/365A61P15/10
CPCA61K31/365A61K31/475A61P15/10A61K2300/00
Inventor 鄢云彪李慧琴刘科金振东
Owner CHENGDU BAIYU PHARMA CO LTD
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