Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method for producing fermentation liquor with high [gamma]-aminobutyric acid content by employing lactic acid bacteria, and application of fermentation liquor in cosmetics

A technology of aminobutyric acid and lactic acid bacteria, applied in cosmetics, cosmetic preparations, fermentation and other directions, can solve the problems of low content of gamma-aminobutyric acid, limited application, limited types and functions of metabolites, etc., to improve dull skin. , The effect of improving skin whiteness, elasticity and moisture

Active Publication Date: 2019-12-20
哈尔滨美华生物技术股份有限公司
View PDF5 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the types and functions of the metabolites after the fermentation of the three fermentation bacteria are limited, and the content of the functional product γ-aminobutyric acid is low, which limits its application in cosmetics

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method for producing fermentation liquor with high [gamma]-aminobutyric acid content by employing lactic acid bacteria, and application of fermentation liquor in cosmetics
  • Preparation method for producing fermentation liquor with high [gamma]-aminobutyric acid content by employing lactic acid bacteria, and application of fermentation liquor in cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] A lactic acid bacterium produces a fermented liquid high in gamma-aminobutyric acid, the preparation method of which is as follows:

[0053] (1) Germinate brown rice and barley until the leaf bud length is 1 / 3 of the seed, heat to 40°C for 5 minutes, stop germination, and mix with mulberry leaves. The mass ratio of brown rice, barley and mulberry leaves is 1:2:1.5, Pulverize to get mixed powder;

[0054] (2) Soak the mixed powder in water according to the mass volume ratio of 0.25:1g / mL, heat at 55°C for 0.5h, then raise the temperature to 60°C, keep it warm for 2h, and filter while it is hot to obtain the filtrate;

[0055] (3) Add glutamic acid with a mass fraction of 0.5% to the filtrate, heat to 105°C to sterilize for 10 minutes, insert Lactobacillus plantarum, inoculate 1.0%, ferment at 35°C for 6 hours, filter, and the filtrate is produced by lactic acid bacteria Fermentation broth high in γ-aminobutyric acid.

[0056] A cosmetic composition, consisting of the f...

Embodiment 2

[0059] A lactic acid bacterium produces a fermented liquid high in gamma-aminobutyric acid, the preparation method of which is as follows:

[0060] (1) Germinate brown rice and barley until the leaf bud length is 2 / 3 of the seed, heat to 50°C for 15 minutes, stop germination, mix with mulberry leaves, the mass ratio of brown rice, barley and mulberry leaves is 2:1:0.5, Pulverize to get mixed powder;

[0061] (2) Soak the mixed powder in water according to the mass volume ratio of 1.1:1g / mL, heat at 57°C for 1h, then raise the temperature to 65°C, keep it warm for 5h, and filter while it is hot to obtain the filtrate;

[0062] (3) Add sodium glutamate with a mass fraction of 2.5% to the filtrate, heat to 121°C for sterilization for 30 minutes, insert Lactobacillus acidophilus with an inoculum size of 10.0%, ferment at 40°C for 24 hours, filter, and the filtrate is Lactic acid bacteria produce a fermented liquid high in GABA.

[0063] A cosmetic composition, which is composed ...

Embodiment 3

[0066] A lactic acid bacterium produces a fermented liquid high in gamma-aminobutyric acid, the preparation method of which is as follows:

[0067] (1) Germinate brown rice and barley until the leaf bud length is 1 / 2 of the seed, heat to 45°C for 10 minutes, stop germination, mix with mulberry leaves, the mass ratio of brown rice, barley and mulberry leaves is 2:2:1, Pulverize to get mixed powder;

[0068] (2) Soak the mixed powder in water according to the mass volume ratio of 0.7:1g / mL, heat at 56°C for 0.75h, then raise the temperature to 62.5°C, keep it warm for 4h, and filter while it is hot to obtain the filtrate;

[0069] (3) Add glutamic acid with a mass fraction of 1.5% to the filtrate, heat to 113°C to sterilize for 20 minutes, insert Lactobacillus casei, inoculate 5.5%, ferment at 38°C for 15 hours, filter, and the filtrate is produced by lactic acid bacteria Fermentation broth high in γ-aminobutyric acid.

[0070] A cosmetic composition, consisting of the followi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of fermentation technologies and cosmetics, in particular to a preparation method for producing fermentation liquor with a high [gamma]-aminobutyric acid content byemploying lactic acid bacteria, and an application of fermentation liquor in cosmetics. The preparation method comprises the following steps of: (1) enabling brown rice and barley to sprout, mixing the sprouted brown rice and barley with folium mori, and smashing the mixture to obtain a mixed powder; (2) adding water into the mixed powder for dipping, and conducting filtering to obtain a filtrate;and (3) adding glutamic acids or / and glutamate into the filtrate, inoculating fermentative bacteria, and conducting filtering to obtain the fermentation liquor. The fermentation liquor has the advantages of high [gamma]-aminobutyric acid content, good use effect and no side effects when the fermentation liquor is applied to cosmetics.

Description

technical field [0001] The invention relates to the fields of fermentation technology and cosmetics, in particular to the production of fermented liquid containing high gamma-aminobutyric acid by lactic acid bacteria and its application in cosmetics. Background technique [0002] γ-aminobutyric acid (GABA), English name: γ-aminobutyric acid, chemical name: 4-aminobutyric acid, aliases: aminobutyric acid, pipecolic acid, widely distributed in animals and plants. Seeds, rhizomes and tissue fluids of plants such as beans, ginseng, and Chinese herbal medicines all contain GABA. In animals, GABA exists almost only in nerve tissue, and the content in brain tissue is about 0.1-0.6mg / gram tissue. GABA is an important neurotransmitter with a variety of physiologically active functions. It has physiological effects on human epidermal cells, such as physiological repair, cell activation, skin rejuvenation and beauty. GABA is also closely related to the quality of sleep and is known a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C12P13/00A61K8/44A61Q19/00C12R1/25C12R1/23C12R1/245C12R1/225
CPCA61K8/44A61K2800/85A61Q19/00C12P13/005
Inventor 梁金钟肖雯娟林枫翔
Owner 哈尔滨美华生物技术股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com