Dynamic human stomach-duodenum in-vitro bionic digestive system

Abstract

The invention discloses a dynamic human stomach-duodenum in-vitro bionic digestive system comprising a heating incubator and an esophagus model, a stomach model, a duodenum model, peristaltic extrusion devices and a digestion emptying unit which are located in the heating incubator, and the esophagus model, the stomach model and the duodenum model are connected with one another; the peristaltic extrusion devices are arranged on the two sides of the esophagus model, the stomach model and the duodenum model respectively and used for achieving bionic movement of the esophagus model, the stomach model and the duodenum model; and the digestion emptying unit comprises a feeding device connected with an inlet of the esophagus model, a digestive juice adding device connected with the stomach modeland the duodenum model, and an emptying device connected with an outlet end of the duodenum model. According to the dynamic human stomach-duodenum in-vitro bionic digestive system in the invention, the digestive process of the stomach and the duodenum of a human body can be truly simulated, accurate test data is provided for researching the digestive system of the human body, and meanwhile animalexperiments and human body experiments can be properly reduced to a certain extent.

Description

technical field [0001] The invention belongs to the field of in vitro digestion simulation. Specifically, the invention relates to a dynamic human stomach-duodenum bionic digestion system in vitro, which is used for equipment capable of simulating the human stomach-duodenum digestion process, and can be used for food and Drug in vitro digestion experiments. Background technique [0002] So far, most of the in vitro simulated digestion and absorption equipment at home and abroad have not played a bionic and real role in the anatomy of the human body, and the stirred reactor (glass vessel) simulated digestive reaction system is commonly used. For example, Chinese patent document CN103740589 discloses a human gastrointestinal bionic system and a simulation experiment method based on the system. This system ignores the stirring principle of the flexible reactor and its interaction with food in the real digestion process. Contents of the invention [0003] Therefore, the techn...

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Problems solved by technology

[0002] So far, most of the in vitro simulated digestion and absorption equipment at home and abroad have not played a bionic and real role in the anatomy of the human body. The commonly used one is the stirred reactor (glass vessel) simulated digestive reaction system

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