Biological analysis method for detecting plasma drug concentration of small-molecule drugs in antibody drug conjugates

Abstract

The invention discloses a biological analysis method for detecting the plasma drug concentration of small-molecule drugs in antibody drug conjugates. A device adopted in the biological analysis methodcomprises a workbench, a feeding device is arranged on the upper side of the workbench, a rotation shaft installed on a hood is arranged over the feeding device, a roller is arranged on the outer side of the rotation shaft, and a plurality of cutters are evenly distributed on the outer side of the roller; supporting columns are arranged on the lower side of the workbench, a supporting plate is arranged at the lower ends of the supporting columns, a plurality of loop bars are arranged on the lower side of the supporting plate, telescopic rods are arranged at the lower ends of the loop bars, abase is arranged at the lower ends of the telescopic rods, and damping springs are arranged on the outer sides of the telescopic rods; and supporting rods are arranged at the right end of the upper side of the supporting plate, a cleaning box is arranged at the upper ends of the supporting rods, a stirring motor is arranged at the lower end of the cleaning box, a stirring shaft installed in the cleaning box is arranged at the output end of the stirring motor, a feeding hopper is arranged at the upper end of the cleaning box, and an oblique discharging plate is arranged at a discharging port. According to the biological analysis method for detecting the plasma drug concentration of the small-molecule drugs in the antibody drug conjugates, the structure is simple, use is convenient, the slicing effect is good, a cleaning function is achieved, the working efficiency is improved, and the service life of the device is prolonged.

Description

technical field [0001] The invention relates to the technical field of slicing devices, in particular to a blood drug concentration biological analysis method for detecting small molecule drugs in antibody-drug conjugates. Background technique [0002] The pharmaceutical industry and the biomedical engineering industry are the two pillars of the modern pharmaceutical industry. The biomedical industry is composed of the biotechnology industry and the pharmaceutical industry. Countries and organizations have very different definitions and boundaries of the biotechnology industry, and even different people often have very different views. Biomedical engineering is the comprehensive application of the principles and methods of life science and engineering science. From the perspective of engineering, it understands the structure, function and other life phenomena of the human body at multiple levels in molecules, cells, tissues, organs and even the entire human body system. Th...

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Problems solved by technology

This type of slicing process has the following problems: it is difficult to maintain a uniform slice thickness of the medicinal materials; the slicing speed is limited and the efficiency is not high enough; the slicing edge is easily damaged, and due to frequent friction of the slicing, the edge of the knife is overheated, which also has a certain impact on the medicinal properties of the Chinese herbal medicine; Most of the cutting edge of the equipment is exposed, which is easy to cause accidental injury to personnel during operation

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