Pancreatic cancer detection reagent, pancreatic cancer detection kit, pancreatic cancer detection device and application
A detection reagent and a technology for pancreatic cancer, applied in the field of pancreatic cancer detection reagents, to achieve the effects of long survival period, good specificity and high detection sensitivity
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[0102] Tumor tissues of 20 pancreatic cancer patients were selected: 10 cases each with shorter survival (sample number 1-10) and better survival (sample number 11-20 months) (overall survival (OS), specific survival See Table 1 for period.
[0103] Table 1. Survival period of 20 lung cancer patients
[0104] sample number 1 2 3 4 5 6 7 8 9 10 OS / month 5 6 8 8 8 10 10 11 12 12 sample number 11 12 13 14 15 16 17 18 19 20 OS / month 20 21 22 22 22 24 26 26 35 51
[0105] Multiplex immunohistochemical analysis of immune cells and immune checkpoint molecular detection was performed on the paraffin sections of tumor tissues of the above 20 cases. Each patient had 6 slices, a total of 6 staining panels, and a total of 18 molecules were labeled. The staining order of each molecule in 18 dyed molecules and 6 panels is:
[0106] Panel1: CD163, CD68, CD4, CD8, CD3;
[0107]Panel2: CD163, CD68, PDL1, CD8, PD1, CD57; ...
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