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Application of Yaoyao rapeseed extract in preparation of medicine for treating pneumonia caused by Klebsiella infection

A technology of Klebsiella and rapeseed, applied in the field of medicine, to achieve the effect of reducing the increase of lung coefficient and the increase of TNF-α

Active Publication Date: 2021-09-24
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] So far, there are no relevant reports at home and abroad on the use of Yao Yao rapeseed extract for the treatment of pneumonia caused by Klebsiella infection

Method used

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  • Application of Yaoyao rapeseed extract in preparation of medicine for treating pneumonia caused by Klebsiella infection
  • Application of Yaoyao rapeseed extract in preparation of medicine for treating pneumonia caused by Klebsiella infection
  • Application of Yaoyao rapeseed extract in preparation of medicine for treating pneumonia caused by Klebsiella infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Application of an extract of yaoyao rapeseed in the preparation of medicine for treating pneumonia caused by Klebsiella infection. Pilea cavaleriei The whole herb of H. Lév.; the drug is prepared into a pharmaceutically acceptable dosage form by adding the extract of Yaoyao rapeseed rape as the active ingredient, adding pharmaceutically acceptable adjuvants or auxiliary ingredients; the pharmaceutically acceptable Dosage forms include tablets, capsules, granules, dropping pills or oral solutions.

[0026] The application of the above-mentioned Yaoyao rapeseed extract in the preparation of medicines for the treatment of pneumonia caused by Klebsiella infection, the said Yaoyao rapeseed extract is the water extract or water-extracted alcohol precipitate of Yaoyao medicine, and the Yaoyao The method for extracting the water extract of rapeseed or the water-extracted alcohol precipitate comprises the following steps:

[0027] (1) Take the rapeseed medicinal material for us...

Embodiment 2

[0031] Application of an extract of yaoyao rapeseed in the preparation of medicine for treating pneumonia caused by Klebsiella infection. Pilea cavaleriei The whole herb of H. Lév.; the drug is prepared into a pharmaceutically acceptable dosage form by adding the extract of Yaoyao rapeseed rape as the active ingredient, adding pharmaceutically acceptable adjuvants or auxiliary ingredients; the pharmaceutically acceptable Dosage forms include tablets, capsules, granules, dropping pills or oral solutions.

[0032] The application of the above-mentioned Yaoyao rapeseed extract in the preparation of medicines for the treatment of pneumonia caused by Klebsiella infection, the said Yaoyao rapeseed extract is the water extract or water-extracted alcohol precipitate of Yaoyao medicine, and the Yaoyao The method for extracting the water extract of rapeseed or the water-extracted alcohol precipitate comprises the following steps:

[0033] (1) Take the rapeseed medicinal material for us...

Embodiment 3

[0037] Application of an extract of yaoyao rapeseed in the preparation of medicine for treating pneumonia caused by Klebsiella infection. Pilea cavaleriei H. Lév. The whole herb; the medicine is prepared into a pharmaceutically acceptable dosage form by adding the extract of the Yaoyao rapeseed rape as the active ingredient and adding pharmaceutically acceptable adjuvants or auxiliary ingredients; the pharmaceutically acceptable dosage form includes tablets capsules, granules, pills or oral solutions.

[0038] The application of the above-mentioned Yaoyao rapeseed extract in the preparation of medicines for the treatment of pneumonia caused by Klebsiella infection, the said Yaoyao rapeseed extract is the water extract or water-extracted alcohol precipitate of Yaoyao medicine, and the Yaoyao The method for extracting the water extract of rapeseed or the water-extracted alcohol precipitate comprises the following steps:

[0039] (1) Take the rapeseed medicinal material for use...

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Abstract

The invention belongs to the technical field of medicines, and in particular relates to the application of a Yao medicine oilseed rape extract in the preparation of a medicine for treating pneumonia caused by Klebsiella infection. The present invention discloses for the first time the application of the extract of the Yao Yao drug in the preparation of a drug for treating pneumonia caused by Klebsiella infection. Antibacterial experiments in vitro show that the extract of the Yao drug can significantly inhibit Klebsiella pneumoniae and pneumoniae The growth of cocci and other bacteria, through the therapeutic effect test of rapeseed on Klebsiella pneumoniae infected mice, the content of various inflammatory factors and the lung index proved that the extract of Yao medicine rapeseed has no effect on mice infected with Klebsiella pneumoniae. Pneumonia has a therapeutic effect; it can be used as a natural antibacterial drug for the treatment of pneumonia caused by Klebsiella infection, thus providing a new way for the treatment of pneumonia caused by Klebsiella infection.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to the application of a Yao medicine oilseed rape extract in the preparation of a medicine for treating pneumonia caused by Klebsiella infection. Background technique [0002] Yaoyao oleracea is Urticaceae plant with corrugated cold water flowers Pilea cavaleriei The whole herb of H. Lév., also known as rock cauliflower, fat slave grass, small rock mustard, frozen grass, malnutrition grass, rock amaranth, fat pig dish, beaten dead, stone cold vegetable, frog legs, distributed in Guangxi, Guangdong, Guizhou , Hunan and other places. Born in the shade of rocky mountains, more common on rocks under forests on hillsides at an altitude of 300-1500 meters. Harvested throughout the year, washed, used fresh or sun-dried. Slightly bitter, cool in nature; returns lung, spleen meridian. Clearing lung heat and relieving cough, inducing diuresis to reduce swelling, detoxifying...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P11/00A61P31/04
CPCA61K36/185A61K2236/331A61K2236/39A61K2236/53A61P11/00A61P31/04
Inventor 庞宇舟冯桥陈晓艺王志萍黎芳蒋雅娴李晓霞刘笑苏佳昇
Owner GUANGXI UNIV OF CHINESE MEDICINE
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