Formula for prevention and treatment of acute severe pancreatitis combined with liver damage
A technology for pancreatitis and liver damage, applied in the field of traditional Chinese medicine formulas for the treatment of acute severe pancreatitis, can solve the problems of poor acceptance of severe patients, inability to treat patients based on syndrome differentiation, high cost of western medicine, etc. convenient effect
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Embodiment 1
[0020] Embodiment 1, a kind of formula for the prevention and treatment of acute severe pancreatitis combined with liver damage, including the prevention phase formula and the treatment phase formula, the specific formula is as follows:
[0021] Prevention stage: Scutellaria baicalensis 0.01-0.05 grams + Salvia miltiorrhiza 0.01-0.015 grams / Kg body weight;
[0022] Treatment stage: Scutellaria baicalensis 0.01-0.05 grams + Salvia miltiorrhiza 0.02-0.03 grams / Kg body weight.
[0023] The specific experimental method is as follows:
[0024] 1. Materials and methods
[0025] 1.1 Grouping of animals: 70 Wistar rats, male or female, weighing (320±50) g.
[0026] They were randomly divided into 12 groups, see Table 1.
[0027] group 4h 8h 24h control group 4 4 4 pancreatitis ASP group 4 4 4 Scutellaria baicalensis + Salvia miltiorrhiza low dose group 4 4 4 Scutellaria baicalensis + Salvia miltiorrhiza high dose group 4 4 4
[0028]...
Embodiment 2
[0050] Embodiment 2, a preparation method of a prescription for the prevention and treatment of acute severe pancreatitis combined with liver damage, the specific method is as follows: 1, extraction: put 40-60 parts of Scutellaria baicalensis pieces and 40-60 parts of Salvia miltiorrhiza into 20- In a container of water at 30°C, add 8 times the total weight of Scutellaria baicalensis and Danshen decoction pieces, soak for 30-60 minutes, decoct and extract the soaked medicinal materials, heat to boiling with fire, and then heat slowly for 2 hours after boiling , the decoction extraction process parameters include: the extraction pressure is 0.06-0.12MPa, and / or the extraction temperature is 100-110°C, and / or the extraction time is 30-60min, the above operation is repeated at least 3 times, and then the above obtained The extracts are mixed;
[0051] 2. Separation: The extract is subjected to solid-liquid separation. The solid-liquid separation adopts high-speed separation and p...
Embodiment 3
[0055] Embodiment 3. A method of using a therapeutic formula for acute severe pancreatitis complicated with liver damage. Take the granules twice a day in the morning and evening with water, and avoid eating stimulating food.
[0056] Analysis of prescriptions and prescriptions: Scutellaria baicalensis: "New Compendium of Materia Medica" says: Scutellaria baicalensis, bitter in taste, calm in gas, cold in nature, can rise or fall, slightly yang in yin, non-toxic. Go into lung meridian, large intestine. Reducing fever and relieving restlessness, purging bladder fire, stopping red dysentery, eliminating red eyes, relieving typhoid fever stagnation and steaming, moistening dryness.
[0057] Danshen: "Materia Medica New Edition" said: slightly cold. Bitter. Non-toxic. The main confidant is evil. Bowel sounds faint like running water. Accumulation of cold and heat. Break the disease and eliminate the lump. Stop bothering and replenish Qi. Danshen is slightly cold. Endowed ...
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