Preparation method of saikosaponin

Abstract

The present invention discloses a preparation method of saikosaponin. Raw materials comprise 10 g of rhizome bupleuri, 120 g of 90% of ethanol, compound biological enzymes, low-carbon alcohol and macroporous adsorption resin. The preparation method is meticulous in steps, firstly, the rhizome bupleuri is crushed, a plant fiber structure is destroyed, during enzymatic hydrolysis, contact areas withan enzymatic hydrolysate can also be increased, an enzymatic hydrolysis speed of the plant fibers in the rhizome is accelerated, the biological enzymes comprise cellulase, protease and pectinase, canconduct the enzymatic hydrolysis of cell walls of the rhizome bupleuri and other biological substances, and fully destroy the original biological structure, so that saponin can be released, then multiple ethanol extractions can extract the saponin from the rhizome bupleuri, then extraction with ethanol is used, an obtained primary material is subjected to twice extraction, and impurities thereinare further separated. The preparation method can obtain the high-purity saponin and content of the fine impurities in the obtained saponin is less than that of the existing saponin.

Description

technical field [0001] The invention discloses a method for preparing saikosaponin, which belongs to the technical field of saikosaponin preparation. Background technique [0002] Saikosaponin is a kind of medicine, which is used for cold and fever, alternating cold and heat, chest and hypochondrium pain, etc., and the shelf life is two years. [0003] Most of the existing saikosaponins have low purity, and their preparation results in many remaining impurities, and some impurities are ignored during the extraction process, resulting in most of the saikosaponins on the market failing to fully exert their efficacy. Contents of the invention [0004] The technical problem to be solved by the present invention is to overcome the fact that most of the existing saikosaponins have low purity, and their preparation has more residual impurities, and some impurities are ignored in the process of extraction, resulting in a large amount of saikosaponins on the market. Most of them f...

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to overcome the fact that most of the existing saikosaponins have low purity, and their preparation has more residual impurities, and some impurities are ignored in the process of extraction, resulting in a large amount of saikosaponins on the market. Most of them fail to give full play to their efficacy, and a preparation method of saikosaponin is provided to solve the above problems