Biomarker for pre-employment screening of workers exposed to noise
A gene marker and noise technology, applied in the field of biotechnology, can solve the problems of body hearing loss, noise-induced deafness, etc., and achieve the effect of high sensitivity and simple operation
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[0029] The present invention will be further explained below in conjunction with the accompanying drawings and specific embodiments.
[0030] Selection of research subjects
[0031] In this study, 1140 noise-exposed workers from 3 large machinery factories were selected, and demographic data and on-site noise exposure data were collected. According to the "Diagnostic Criteria for Occupational Noise Deafness" (GBZ49-2007), the hearing examination was carried out for the research objects. The workers whose binaural average high-frequency hearing threshold ≥ 25dB was selected as the hearing loss group, and the workers whose hearing loss was less than 25dB were selected as the control group, and the research objects were all Han nationality. The inclusion criteria for all research objects are: (1) Workers who have been exposed to steady-state noise environments for more than three years; (2) Workers who have not been exposed to chemical harmful factors such as heavy metals, organi...
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