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Coagulation testing for low sample volumes

A detection unit, a technology for blood samples, applied in the field of coagulation detection with low sample volume, which can solve problems such as management of treatment methods, coagulation risks, and implementation risks that are difficult to handle and control coagulation

Active Publication Date: 2022-07-26
THERANOS IP CO LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Blood clotting abnormalities are very dangerous and treatments to address and control blood clotting are difficult and dangerous to administer

Method used

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  • Coagulation testing for low sample volumes
  • Coagulation testing for low sample volumes
  • Coagulation testing for low sample volumes

Examples

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Embodiment Construction

[0089] Before examples of the invention are described, it should be understood that such examples are provided by way of illustration only and that various alternatives to the examples of the invention described herein may be used in practice. Numerous variations, modifications and substitutions will occur to those skilled in the art without departing from the invention.

[0090] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Although methods and materials similar or equivalent to those described herein can be used in practice or in the examination of the present invention, suitable methods and materials are described below. In case of conflict, the patent designations, including definitions, will control. Moreover, the materials, methods, and demonstrations are for illustrative purposes only, and are not intended to be limiting. Numerou...

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Abstract

Some components and methods for the determination of coagulation parameters using trace amounts of blood are provided. Advantageously, the methods described herein can be assayed in a single drop of blood (approximately 20 [mu]L), while generally reserving a sufficient amount of sample for performing other assays, optionally in a multiplex assay format. The method and device do not require an experienced operator and can be performed in a designated service location, which is very important for the management and treatment of coagulation abnormalities.

Description

[0001] This application claims the benefit of U.S. Provisional Application Serial No. 61 / 673,227, filed July 18, 2012, which is incorporated herein by reference in its entirety. Background technique [0002] Coagulation is a complex process by which blood or plasma forms a blood clot. It is an important part of the body's homeostasis, stops blood loss from damaged blood vessels, and the walls of damaged blood vessels are covered by platelets and fibrin-containing blood clots to stop bleeding and begin repair of damaged blood vessels. Since insufficient coagulation can lead to an increased risk of bleeding (bleeding), and excessive coagulation can lead to obstructive blood clots (thrombosis), the coagulation process is tightly controlled and highly conserved throughout the organism. [0003] Coagulation abnormalities are very dangerous, and treatments to manage and control blood clotting are difficult to manage and risky to implement. In addition, many patients take long-term ...

Claims

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Application Information

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IPC IPC(8): G01N33/49G01N33/86G01N21/51
CPCG01N33/4905G01N33/86C12Q1/56G01N21/84G01N33/582G01N2333/75
Inventor M·戴耶尔S·阿内卡尔P·帕特尔I·吉本斯E·霍姆斯
Owner THERANOS IP CO LLC
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