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System matrix generation and processing method for accelerating positron image reconstruction

A system matrix and image reconstruction technology, which is applied in computerized tomography scanners, instruments for radiological diagnosis, medical science, etc., can solve problems such as detection occasions that cannot meet real-time requirements, time-consuming, slow image reconstruction process, etc.

Active Publication Date: 2019-03-22
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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Problems solved by technology

For the response line that is far away from the pixel and does not pass through the pixel, the probability of the positron annihilating on this pixel to generate the response line is 0, which is called zero probability data, which also leads to the large analytical method system matrix Most of the data recorded in is zero-projection data, which not only takes up a lot of storage space, but also performs iterative calculation processing on zero-probability data during image reconstruction, making the image reconstruction process slow, time-consuming, and resource-intensive. Unable to meet some detection occasions with high real-time requirements

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  • System matrix generation and processing method for accelerating positron image reconstruction
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  • System matrix generation and processing method for accelerating positron image reconstruction

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[0038] specific implementation plan

[0039] The technical solutions of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0040] Image reconstruction is the process of reconstructing a tomographic image through a sinogram to form a slice map. The system matrix is ​​used as a bridge to reconstruct the sinogram into a slice map, and records the quantized length of each response line passing through each pixel to reflect the positron in the slice map. Annihilation occurs on each pixel of , yielding a probability distribution of different response lines. For the convenience of illustration, assume a miniature positron detection device, such as figure 1 As shown, a 4×4 slice image is detected in the field of view in the miniature positron detection ring, and one pair of detectors AA' of the detection device receives coincident data, that is, the data of the response line of AA', which is determined by According to the princip...

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Abstract

The invention discloses a system matrix generation and processing method for accelerating positron image reconstruction, and belongs to the field of ray detection imaging. The method includes the following steps: (1) proposing a new system matrix establishment method instead of the system matrix establishment method in an original MLEM algorithm; (2) proposing a method for accelerating the processof positron image reconstruction by processing system matrix based on the MLEM algorithm. The method improves the overall efficiency of the positron image reconstruction process.

Description

technical field [0001] The invention relates to a system matrix generation and processing method for accelerating positron image reconstruction, belonging to the field of radiation detection and imaging. Background technique [0002] PET (Posintron Emission Tomography, Positron Emission Computed Tomography) injects a radioactive tracer into the test object and detects the annihilation reaction generated by the positrons emitted by the decay of the tracer. Physiological metabolism, neural receptors, etc. for localization, diagnosis and evaluation. PET detection is mainly divided into four steps: [0003] 1. Line of coincidence detection: By detecting the paired γ produced by the positron annihilation reaction, a large amount of Line of Response (LOR) data is obtained. [0004] 2. Image reconstruction: convert a large amount of response line data into sinogram data containing projection information. [0005] 3. Image reconstruction: restore the sinogram data to a planar sli...

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Application Information

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IPC IPC(8): A61B6/03
CPCA61B6/037A61B6/5217
Inventor 林琦琛姚敏赵敏郭瑞鹏徐君
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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