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Itching-relieving liquid and preparation method thereof

The technology of a solution and an ethanol solution is applied in the directions of pharmaceutical formulations, medical preparations without active ingredients, medical preparations containing active ingredients, etc. The method is simple and the production cost is low

Inactive Publication Date: 2019-03-01
XINJIANG CICON HABO WEI PHARMA RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But, the effect of the antipruritic liquid prepared by single taking sipayi gum liquid dregs as raw material is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Including the following components in volume percentage: 40% ethanol solution of Xipayi gum residue extract, 20% ethanol solution of Sophora flavescens extract, 10% ethanol solution of borneol, 0.2% peppermint oil solution, the rest is water.

[0043] The specific steps are as follows:

[0044] (1) Preparation of ethanol solution of Sophora flavescens extract: Weigh 30 g of Sophora flavescens decoction pieces, add 300 ml of ethanol solution with a mass fraction of 60%, soak for 60 minutes, sonicate for 20 minutes, and filter to obtain an ethanol solution of Sophora flavescens extract.

[0045] (2) Preparation of the ethanol solution of Xipayi Guinggu Liquid Extract: Weigh 12.5g of Xipayi Guinggu Liquid and add 400ml of 95% ethanol solution. After ultrasonic dissolution, Xipayi can be obtained. Ethanol solution of gingival fluid residue extract.

[0046] (3) Preparation of borneol ethanol solution: weigh 1 g of borneol, add 100ml of ethanol solution with a mass fraction of 95%,...

Embodiment 2

[0052] Including the following components by volume percentage: 8% ethanol solution of Xipayi gum residue extract, 5% ethanol solution of Sophora flavescens extract, 10% ethanol solution of borneol, 0.1% peppermint oil solution, and the rest are water.

[0053] The specific steps are as follows:

[0054] (1) Preparation of ethanol solution of Sophora flavescens extract: Weigh 30 g of Sophora flavescens decoction pieces, add 600ml of ethanol solution with a mass fraction of 60%, soak for 50 minutes, sonicate for 22 minutes, and filter to obtain an ethanol solution of Sophora flavescens extract.

[0055] (2) Preparation of the ethanol solution of Xipayi Guing Ging Liquid residue extract: Weigh 0.65 g of Xipayi Guing Gingival Liquid residue, add 4ml of 95% ethanol solution, and dissolve it by ultrasound to obtain Xipayi Gu Ethanol solution of gingival fluid residue extract.

[0056] (3) Preparation of borneol ethanol solution: weigh 0.05 g borneol, add 5 ml of ethanol solution with a ma...

Embodiment 3

[0062] Including the following components in volume percentages: 8% ethanol solution of Xipayi gum residue extract, 5% ethanol solution of Sophora flavescens extract, 8% ethanol solution of borneol, 0.1% peppermint oil solution, and the rest are water.

[0063] The specific steps are as follows:

[0064] (1) Preparation of ethanol solution of Sophora flavescens extract: Weigh 30 g of Sophora flavescens decoction pieces, add 270 ml of ethanol solution with a mass fraction of 60%, soak for 70 minutes, sonicate for 18 minutes, and filter to obtain an ethanol solution of Sophora flavescens extract.

[0065] (2) Preparation of the ethanol solution of Xipayi Guinggu Liquid Extract: Weigh 1.25 g of Xipayi Guinggu Liquid residue, add 4ml of 95% ethanol solution, and dissolve it by ultrasound to obtain Xipayi Ethanol solution of gingival fluid residue extract.

[0066] (3) Preparation of borneol ethanol solution: weigh 0.05 g borneol, add 5 ml of ethanol solution with a mass fraction of 95%, ...

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Abstract

The invention discloses itching-relieving liquid and a preparation method thereof. The itching-relieving liquid contains, by volume, 8-40% of a collutorymaxillary decoction dreg extract ethanol solution, 5-20% of a sophora flavescens extract ethanol solution, 8-12% of a borneol ethanol solution, 0.1-0.2% of a peppermint oil solution and the balance water, wherein the peppermint oil solution contains peppermint oil, talcum powder and water. The preparation method of the above-mentioned itching-relieving liquid is also disclosed in the invention. The itching-relieving liquid uses a collutorymaxillary decoction dreg extract as a main material and uses a sophora flavescens extract as an auxiliary material, and the bacteriostatic and itching-relieving effects of the itching-relieving liquid isimproved. The residual value of decoction dregs is fully utilized, the use method is simple, the preparation method is simple, the manufacturing cost is low, and the itching-relieving liquid is nontoxic, free from extraneous odor and non-irritant and has a good itching-relieving effect.

Description

Technical field [0001] The invention belongs to the technical field of external medicine, and specifically relates to an antipruritic liquid and a preparation method thereof. Background technique [0002] Thousands of tons of Xipayi gum slag are produced every year in pharmaceutical factories. Most of the slag is burned as fuel or discarded as garbage. Random stacking or unreasonable disposal may cause serious environmental pollution problems and also affect resources. It is a great waste. [0003] The main drug in Xipayi Guging Liquid Medicine Residue is gallbladder, which contains gallic tannin, gallic acid, ellagic acid and other chemical components, which has antibacterial and antipruritic, antioxidant, antiviral, antitumor and other pharmacological effects. Studies have found that there are a large number of effective chemical components remaining in the residue of Xipayi Guging Liquid, which has high medicinal and commercial value. Therefore, we propose a method for prepari...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61K9/08A61P17/04A61K35/64A61K31/045
CPCA61K9/0014A61K9/08A61K31/045A61K35/64A61K36/489A61K36/534A61K47/10A61K2236/333A61K2236/53A61P17/04A61K2300/00
Inventor 季志红陈金成李柯翱马璇
Owner XINJIANG CICON HABO WEI PHARMA RES INST
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