Self-driven particle counter and counting method thereof

Abstract

The invention discloses a self-driven particle counter and a counting method thereof. The self-driven particle counter comprises a micro-channel plate, two microelectrodes, a friction nanogenerator and a signal collecting and processing device, wherein the micro-channel plate is provided with a micro-channel for particles to be counted passing; the two microelectrodes are correspondingly and oppositely arranged on the upper portion and lower portion of the micro-channel; the friction nanogenerator is electrically connected with the two microelectrodes, and output electric signals are loaded between the two microelectrodes; and the signal collecting and processing device collects and processes electric pulse signals of the two microelectrodes during the particle passing, and self-driven counting is realized. The self-driven particle counter has high counting precision, is convenient to operate, has wide preparation material sources and low economic cost, guarantees the personnel safetyof users, and realizes the self-driven counting; and the micro-channel is easy to process, operation is convenient at a macro level, and the blockage of the channel is easy to clean.

Description

technical field [0001] The disclosure belongs to the technical field of counting micron-sized particles and micro-flow channels, and relates to a self-driven particle counter and a counting method thereof. Background technique [0002] For micron-sized particles, counting their number becomes an indispensable part of life science research, industry, agriculture, diagnosis and other medical treatment. Taking cell counting as an example, there are mainly two types of existing particle counters, one is a blood cell counting instrument based on the "Coulter principle", that is, the resistance detection method; the other is a flow cytometer or a somatic cell counting instrument. The instrument is based on the principle of fluorescence flow counter. [0003] The resistance detection method is to place a micropore in the liquid to be tested, and add constant current or voltage electrodes at both ends of the micropore. When the particles in the liquid pass through the micropore, th...

AI Technical Summary

Problems solved by technology

This kind of flow cytometer or somatic cell counter still needs an external power source to generate a laser beam, which requires a lot of power consumption, and the steps of fluorescent staining, flow chamber outflow and cell arrangement before cell counting are relatively cumbersome; in addition, The preparation of the instrument is expensive, and the market price is in the millions

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