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Beam evaluation method, device, equipment and storage medium for boron neutron capture therapy

A boron neutron capture and neutron beam technology, which is used in the field of equipment and storage media, devices, and beam evaluation methods for boron neutron capture therapy, and can solve problems such as low efficiency, high complexity, and long time consumption.

Active Publication Date: 2020-12-22
国科中子医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, due to the high complexity of the neutron shaping device, it takes a long time to adjust the neutron shaping device each time, resulting in a serious waste of manpower and material resources and low efficiency

Method used

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  • Beam evaluation method, device, equipment and storage medium for boron neutron capture therapy
  • Beam evaluation method, device, equipment and storage medium for boron neutron capture therapy
  • Beam evaluation method, device, equipment and storage medium for boron neutron capture therapy

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Embodiment 1

[0032] figure 1 It is a flow chart of a beam evaluation method for boron neutron capture therapy provided by Embodiment 1 of the present invention. This embodiment is applicable to various situations of beam evaluation for boron neutron capture therapy, and the method can be implemented by the present invention The example provides a beam evaluation device for boron neutron capture therapy, which can be implemented in the form of software and / or hardware, and can be integrated into any device that provides the beam evaluation function for boron neutron capture therapy. For example, it can be a computer. Such as figure 1 shown, including:

[0033] S110. In the same epithermal neutron beam, acquire a neutron energy spectrum to be evaluated and a photon energy spectrum to be evaluated.

[0034] Due to the wide energy range of neutron beams produced after proton targeting, including fast neutrons, thermal neutrons, epithermal neutrons, etc., epithermal neutrons need to be used ...

Embodiment 2

[0057] Figure 2A It is a flowchart of a beam evaluation method for boron neutron capture therapy provided by Embodiment 2 of the present invention. This embodiment also includes a first depth dose model, a second depth dose model and a third depth dose model on the basis of the above embodiment. Construction of depth dose models.

[0058] Correspondingly, the method of this embodiment includes:

[0059] S210. Obtain multiple groups of monoenergetic neutrons with different energies from the neutrons in the preset energy range.

[0060] Wherein, the neutron of preset energy range can be preset energy range is 10e -9 Neutrons from MeV to 20MeV. Since the energy range of the neutron energy spectrum to be evaluated detected at the outlet of the neutron shaping device can be in any range of the preset energy range, the first depth dose model and the second depth dose model are trained using neutrons in the preset energy range , which can cover the situation of the neutron spect...

Embodiment 3

[0122] Figure 3AIt is a flow chart of a beam evaluation method for boron neutron capture therapy provided by Embodiment 3 of the present invention. This embodiment is optimized on the basis of the above-mentioned embodiments, and provides an optimized data set passing through the multiple sets of first curves. . The multiple sets of second curve data and the multiple sets of third curve data are used to determine the dominant depth and treatment gain to evaluate the treatment effect of the epithermal neutron beam.

[0123] Correspondingly, the method of this embodiment includes:

[0124] S310. In the same epithermal neutron beam, acquire a neutron energy spectrum to be evaluated and a photon energy spectrum to be evaluated.

[0125] S320. Input the energy values ​​of multiple groups of monoenergetic neutrons in the neutron energy spectrum to be evaluated into the first depth dose model and the second depth dose model respectively, so as to obtain multiple sets of first curve...

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Abstract

The embodiment of the invention discloses a beam evaluation method apparatus, and equipment for boron neutron capture therapy, and a storage medium. The method comprises the following steps: acquiringa neutron energy spectrum to be evaluated and a photon energy spectrum to be evaluated in the same epithermal neutron beam; inputting energy values of a plurality of sets of monoenergetic neutrons inthe neutron energy spectrum to be evaluated into a first depth dose model and a second depth dose model, to obtain a plurality of sets of first curve data and a plurality of sets of second curve data, and sequentially inputting energy values of a plurality of sets of single-energy photons in the photon energy spectrum to be evaluated into a third depth dose model to obtain a plurality of sets ofthird curve data; through the plurality of sets of first curve data, determining the plurality of sets of second curve data and the plurality of sets of third curve data, the dominant depth and the therapeutic gain to evaluate the therapeutic effect of the epithermal neutron beam, so that the evaluation efficiency of the therapeutic effect of the epithermal neutron beam is effectively improved, and the beneficial effect of the rapid adjustment of the neutron shaping device is realized.

Description

technical field [0001] Embodiments of the present invention relate to the technical field of radiotherapy, and in particular to a beam evaluation method, device, equipment and storage medium for boron neutron capture therapy. Background technique [0002] With the rapid development of modern medical technology, boron neutron capture therapy has been widely used in clinical medicine. [0003] BNCT (Boron Neutron Capture Therapy, Boron Neutron Capture Therapy) is a bio-targeted radiotherapy mode with "inherent" safety, by injecting non-toxic boron-containing drugs with pro-tumor tissue into human blood, waiting for boron drugs to After being enriched in tumor tissue, epithermal neutrons are used to irradiate the tumor site. Epithermal neutrons enter human tissue and slow down into thermal neutrons, which can interact with 10 The B nuclide undergoes a radiation capture reaction, releasing α particles ( 4 He) and lithium particles ( 7 Li). Due to the short range of these pa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N5/10
CPCA61N5/103A61N5/1048A61N5/1077A61N2005/1021A61N2005/109
Inventor 黄红冷志涛
Owner 国科中子医疗科技有限公司
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