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Cooperative pulse irreversible electropiercing device

A technology of a perforation device and a pulse generating circuit, which is applied in the field of medical devices, can solve problems such as low treatment efficiency of large-sized tumors, and achieve the effects of improving irreversibility, expanding ablation area, and improving treatment efficiency.

Active Publication Date: 2019-01-04
CHONGQING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present disclosure is to provide a coordinated pulsed irreversible electroporation device for at least partially overcoming the problem of low treatment efficiency for large-sized tumors due to the limitations and defects of related technologies

Method used

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  • Cooperative pulse irreversible electropiercing device
  • Cooperative pulse irreversible electropiercing device
  • Cooperative pulse irreversible electropiercing device

Examples

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Embodiment Construction

[0077] Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments may, however, be embodied in many forms and should not be construed as limited to the examples set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete and will fully convey the concept of example embodiments to those skilled in the art. The described features, structures, or characteristics may be combined in any suitable manner in one or more embodiments. In the following description, numerous specific details are provided in order to give a thorough understanding of embodiments of the present disclosure. However, those skilled in the art will appreciate that the technical solutions of the present disclosure may be practiced without one or more of the specific details, or other methods, components, devices, steps, etc. may be adopted. In other instances, well-known technical solutions have not bee...

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Abstract

The invention discloses a cooperative pulse irreversible electroporation device which can be used for ablating tumor cells, and relates to the technical field of medical devices. The Cooperative pulseirreversible electroporation device mainly comprises a synergistic pulse generation circuit and at least one pair of electrodes, wherein the synergistic pulse generation circuit is used for outputting synergistic pulses including a first pulse of a high voltage / narrow pulse width and a second pulse of a low voltage / wide pulse width to the electrode for ablating tumor cells through the electrodes.The cooperative pulse irreversible electroporation device provided by an embodiment of that present disclosure can improve the therapeutic efficiency of a mass tumor.

Description

technical field [0001] The present disclosure relates to the technical field of medical devices, in particular, to an irreversible electroporation device capable of outputting coordinated pulses. Background technique [0002] There are many therapeutic instruments for cancer. In recent years, with the continuous development of pulsed bioelectricity, tumor therapeutic instruments based on electric field pulse technology have attracted extensive attention from researchers in the field of bioelectromagnetics due to their non-thermal and minimally invasive biomedical effects. focus on. [0003] In the application of electric field pulse technology, irreversible electroporation technology is a new application method. Irreversible electroporation refers to sending electric field pulses to the cells in the target area (typical pulse parameters are: field strength 1500-3000V / cm, pulse width 100μs, repetition frequency 1Hz, pulse number 70-120, unipolar square wave electric field pu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/12A61B18/14
CPCH03K3/02A61B18/12A61B18/1206A61B18/1402A61B2018/1226A61B2018/00892A61B2018/00827A61B2018/00595A61B2018/00589A61B2018/00613A61B18/14A61B2018/00577
Inventor 姚陈果董守龙吕彦鹏赵亚军刘红梅
Owner CHONGQING UNIV
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