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Extract for promoting lipid metabolism of liver, resisting inflammation and reducing enzyme content, and preparation method thereof

A lipid metabolism and extract technology, which is applied in anti-inflammatory agents, food extraction, medical preparations containing active ingredients, etc., can solve the problems of liver lipid metabolism disorder, reduced therapeutic effect, and increased liver burden, etc., to achieve inhibition Amplify the inflammatory signal, reduce the expression level, improve the effect of liver lipid accumulation and inflammatory response

Inactive Publication Date: 2019-01-01
CHANGCHUN HEALTH FUTURE MEDICINE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology helps promote hepatitis B virus replication while reducing excessive bile salt concentration in patients' body fluids. By mixing certain types of oils containing these compounds together, they become more effective at stimulate immune responses against viruses like Hepato Virus or Human Immunodeficiency Virus type 1 compared to other methods such as adding different drugs alone. Additionally, this new extraction technique allows us to isolate specific molecules from each component separately without affecting their function when combined. Overall, this innovative technical results enhance the efficacy of existing treatments used to prevent diseases caused by harmful lipids.

Problems solved by technology

This patented technical problem addressed in this patents relates to finding ways to prevent or cure diseases caused due to accumulation of harmful substances like fats in the form of deposited particles called cholesterols within cells lining them.

Method used

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  • Extract for promoting lipid metabolism of liver, resisting inflammation and reducing enzyme content, and preparation method thereof
  • Extract for promoting lipid metabolism of liver, resisting inflammation and reducing enzyme content, and preparation method thereof
  • Extract for promoting lipid metabolism of liver, resisting inflammation and reducing enzyme content, and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] This embodiment provides an extract that promotes liver lipid metabolism, anti-inflammation and enzyme reduction, comprising the following steps:

[0039] (1) Preparation of matsutake enzymatic hydrolyzate

[0040] Dry matsutake at a temperature of 60°C for 4 hours and then pulverize it to obtain matsutake powder; mix the matsutake powder with distilled water at a mass ratio of 2:1, let stand at 4°C for 10 hours, and then stir at a speed of 40r / min 3h, obtain the matsutake homogenate; centrifuge the matsutake homogenate with a rotating speed of 5000rpm for 55min, add papain, cellulase and pectinase to the supernatant and mix the mixture with a mass ratio of 1:1:1 in Under the condition of 35°C, the enzymatic hydrolysis was carried out for 3 hours to obtain matsutake enzymatic hydrolyzate;

[0041] (2) Preparation of extracts that promote liver lipid metabolism, anti-inflammatory and enzyme reduction

[0042] After the yeast is activated, it is cultured to obtain a see...

Embodiment 2

[0044] This embodiment provides an extract that promotes liver lipid metabolism, anti-inflammation and enzyme reduction, comprising the following steps:

[0045] (1) Preparation of matsutake enzymatic hydrolyzate

[0046] Dry matsutake at a temperature of 90°C for 2 hours and then pulverize it to obtain matsutake powder; mix the matsutake powder with distilled water at a mass ratio of 4:3, leave it at 6°C for 14 hours, and stir at a speed of 60r / min 1h, obtain the matsutake homogenate; centrifuge the matsutake homogenate with a rotating speed of 7000rpm for 35min, add papain, cellulase and pectinase to the supernatant and mix the mixture formed with a mass ratio of 1:2:2. Enzymolysis at 40°C for 2 hours to obtain matsutake enzymolysis solution;

[0047] (2) Preparation of extracts that promote liver lipid metabolism, anti-inflammatory and enzyme reduction

[0048] After the yeast is activated, it is cultivated to obtain a seed liquid; add 1000 mL of the matsutake enzymatic sol...

Embodiment 3

[0050] This embodiment provides an extract that promotes liver lipid metabolism, anti-inflammation and enzyme reduction, comprising the following steps:

[0051] (1) Preparation of matsutake enzymatic hydrolyzate

[0052] Dry matsutake at a temperature of 80°C for 3 hours and then pulverize it to obtain matsutake powder; mix the matsutake powder with distilled water at a mass ratio of 3:2, let stand at 5°C for 12 hours, and then stir at a speed of 50r / min 2h, obtain the matsutake homogenate; centrifuge the matsutake homogenate with a rotating speed of 6000rpm for 45min, add papain, cellulase and pectinase to the supernatant and mix the mixture with a mass ratio of 1:2:1 in Enzymolysis at 38°C for 2.5 hours to obtain matsutake enzymolysis solution;

[0053] (2) Preparation of extracts that promote liver lipid metabolism, anti-inflammatory and enzyme reduction

[0054] After the yeast is activated, it is cultivated to obtain a seed liquid; add 1000 mL of the matsutake enzymati...

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Abstract

The invention relates to an extract for promoting lipid metabolism of the liver, resisting inflammation and reducing the enzyme content, and a preparation thereof. The preparation method comprises thesteps that firstly, multiple active substances in matsutake are extracted; and then the active substances are mixed with yeast for fermentation culture, so that the live yeast digests, absorbs and converts the active substances into substances of an organic mode closer to original biological activity and nutrition, accordingly the absorption mechanism is enhanced, and the biological value is improved. Animal experiments prove that the extract provided by the invention has a positive effect on regulating the blood lipid level, can inhibit amplification of inflammatory signals so as to improvelipid accumulation of the liver and inflammatory responses, and accordingly plays a inflammation resistant role; and the extract can effectively reduce the content of GOT and GPT in serum of a mouse with non-alcohol fatty liver disease and has the effect of relieving hepatocyte injury. In the preparation method provided by the invention, extracting the active components of the matsutake through chemical components is avoided, the preparation process is simple, and the large-scale production requirement is met.

Description

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Claims

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Application Information

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Owner CHANGCHUN HEALTH FUTURE MEDICINE TECH CO LTD
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