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Marine fish oligopeptide low-residue nutritional formula product, its preparation method and use

A marine fish oligopeptide and nutritional formula technology, which is applied in the fields of application, food ingredients, and food ingredient functions, can solve problems such as incomplete nutritional supply, difficult absorption of nutrients, and increased difficulty in colonoscopy operations.

Active Publication Date: 2022-03-29
北京麦孚医学科技有限公司 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] (3) Increased operation time of colonoscopy
[0012] (4) The difficulty of colonoscopy operation increases
[0013] (5) Colonoscopy is often not completed
Inadequate bowel preparation resulted in a 19.3% decrease in colonoscopy completion rates: colonoscopies with low-quality colonoscopies had significantly lower completion rates than high-quality and moderate-quality colonoscopies; colonoscopy completion rates compared with high-quality colonoscopies Decreased by 19.3%, the difference is statistically significant (Froehlich F, Wietlisbach V, Gonvers JJ, et al. Gastrointest Endosc, 2005, 61(3): 378-384.)
[0014] (6) Inspection costs increase
The formula has a single nutritional component, lacks vitamins, minerals and fat, and the nutritional supplement is not comprehensive
[0021] (2) The cellulose content is not low enough, and the intestinal cleanliness cannot meet the requirements
CN103431391A discloses a comprehensive nutritional powder formula, which contains corn fiber powder, which is not suitable for intestinal cleansing preparation
[0023] (3) It is not easy to absorb, and it is easy to cause intestinal gas production and flatulence, which will increase the intestinal air bubbles and increase the difficulty of colonoscopy operation
[0024] For example, CN1290443C records a kind of enteral full-nutrition emulsion, which is mainly suitable for patients with nutritional intake disorders. Its protein components mainly come from casein preparations with slow absorption and high cost. prone to gas and flatulence

Method used

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  • Marine fish oligopeptide low-residue nutritional formula product, its preparation method and use
  • Marine fish oligopeptide low-residue nutritional formula product, its preparation method and use
  • Marine fish oligopeptide low-residue nutritional formula product, its preparation method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0152] Example 1: Low-residue nutritional formula product 1

[0153] In every 1000g of the product in this example, as vitamins, it contains: 1.6g of sodium L-ascorbate, 0.23g of nicotinamide, 0.0021g of folic acid, 0.5g of dl-α-tocopheryl acetate, 0.1g of calcium D-pantothenate, and 0.17g of riboflavin g, pyridoxine hydrochloride 0.34g, thiamine hydrochloride 0.02g, retinyl acetate 0.06g, cholecalciferol 0.03g, phytonadione 0.0007g, cyanocobalamin 0.00007g, D-biotin 0.00015g.

[0154] In every 1000g of the product in this embodiment, as minerals, it contains: 0.2g of ferrous sulfate, 0.2g of zinc sulfate, 15g of magnesium sulfate and 2.2g of calcium carbonate. These minerals are mixed evenly with 20g of maltodextrin as embedding agent.

[0155] The amount of raw materials per 1000g product: marine fish oligopeptide 221g, rice protein 33g, maltodextrin 100g (including maltodextrin as embedding agent), fat 320g, sodium carboxymethylcellulose 16g, vitamins and minerals The amo...

Embodiment 2

[0157] Example 2: Low-residue nutritional formula product 2

[0158] In every 1000g of the product in this example, as vitamins, it contains: 1.5g of sodium L-ascorbate, 0.18g of nicotinamide, 0.0017g of folic acid, 0.4g of dl-α-tocopheryl acetate, 0.07g of D-calcium pantothenate, and 0.1 g of riboflavin g, pyridoxine hydrochloride 0.2g, thiamine hydrochloride 0.016g, retinyl acetate 0.04g, cholecalciferol 0.03g, phytonadione 0.0005g, cyanocobalamin 0.00006g, D-biotin 0.00012g.

[0159] In every 1000g of the product in this embodiment, as minerals, it contains: 0.15g of ferrous sulfate, 0.15g of zinc sulfate, 13g of magnesium sulfate and 1.9g of calcium carbonate. These minerals are mixed evenly with 20g of maltodextrin as embedding agent.

[0160] The amount of raw materials: marine fish oligopeptide 210g, rice protein 33g, fructose 250g, fat 355g, sodium carboxymethylcellulose 16g, the amount of vitamins and minerals as above, the balance is maltodextrin, the fat powder is...

Embodiment 3

[0162] Embodiment 3: sensory evaluation experiment

[0163] (1) Sensory evaluation volunteers: 30 colonoscopy subjects and 20 intestinal postoperative patients. For colonoscopy subjects, take the formula product of the present invention with three meals a day before colonoscopy, 1-2 bags each time, and take it with 200ml of warm boiled water. For patients after bowel surgery, take it with three meals a day after surgery, 1-2 bags each time, and take it with 200ml of warm water.

[0164] (2) The results of sensory experience evaluation of colonoscopy subjects are shown in Table 2.

[0165] Table 2: Microscopic sensory evaluation

[0166] Taste number of people odor number of people Adverse event number of people taste good 22 smells good 24 bloating 0 taste better 8 better smell 5 feel sick and vomit 0 average taste 0 can tolerate 1 Dizziness and palpitations 0 bad taste 0 intolerable 0

[0167] (3) T...

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Abstract

The invention provides a low-residue nutritional formula product, its preparation method and its use. The product does not add dietary fiber, and is suitable for intestinal examination and intestinal surgery patients who need to prepare for intestinal cleaning. The product contains proteins, carbohydrates, fats, minerals and vitamins, uses marine fish oligopeptides with smaller molecular weights to replace collagen, and provides more easily absorbed nutrients while maintaining extremely low slag, so that it can be cleaned and reduced. Provide sufficient nutrition for the patient while producing intestinal gas. Compared with conventional intestinal cleansing treatment methods, the product of the invention has high intestinal cleanliness, high detection rate of intestinal adenomas and polyps, less gas production, good nutritional support, and high applicability to patients.

Description

technical field [0001] The invention relates to a special medical low-residue nutritional formula product, its preparation method and its application. Background technique [0002] Colorectal cancer, colorectal cancer, and colorectal polyps are types of intestinal lesions with high risk and high incidence. [0003] Colorectal cancer is a malignant tumor originating from the intraepithelium of the colorectal mucosa, and is one of the most common malignant tumors in clinic. There are more than 250,000 new cases of colorectal cancer in my country every year. According to the "China Tumor Registration Annual Report", colorectal cancer is the second most common digestive tract tumor in my country's tumor registration areas in 2009, second only to gastric cancer. No. 5 in cancer mortality. In the past 20 years, the incidence of colorectal cancer in my country has continued to rise, the incidence of colon cancer has increased significantly, and the incidence of rectal cancer has ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/00
CPCA23L33/40A23V2002/00A23V2200/32
Inventor 冯予春覃倩倩刘德恽陈璐璐
Owner 北京麦孚医学科技有限公司
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