Ultrasonic, photoacoustic and fluorescent three-mode imaging system

Abstract

The invention provides an ultrasonic, photoacoustic and fluorescent three-mode imaging system. The ultrasonic, photoacoustic and fluorescent three-mode imaging system comprises a laser light source module, a motion scanning module, a data acquisition module and a control processing module; the laser light source module is used for providing pulsed laser radiation to an imaging sample and enablingthe imaging sample to generate photoacoustic and fluorescent signals and sending synchronous trigger signals to the data acquisition module and the control processing module; the motion scanning module is used for performing three-dimensional scanning on the sample according to preset motion parameters; the data acquisition module is used for acquiring the photoacoustic / ultrasonic / fluorescent signals generated from the sample; the control processing module is used for receiving trigger pulse signals of a pulsed laser light source, enabling a motion scanning device to scan a target sample according to control instruments, processing received data of the target sample and fusing photoacoustic / ultrasonic / fluorescent images to acquire multimodal reconstructed images. By the arrangement, scanning time in imaging is reduced, and imaging resolution and imaging speed of the imaging system are increased.

Description

technical field [0001] The invention relates to the technical field of photoacoustic imaging, in particular to an ultrasound, photoacoustic and fluorescence three-mode imaging system. Background technique [0002] Photoacoustic Imaging (PAI) is a new type of non-destructive biomedical imaging method based on the difference in optical absorption characteristics inside biological tissues and using ultrasound as the information carrier. It has the high contrast characteristics of pure optical imaging and pure The deep penetrating nature of ultrasound imaging. Photoacoustic imaging detects the photoacoustic signal generated by the light absorber in biological tissue due to the instantaneous thermoelastic effect, replaces photon detection with sound waves, avoids the influence of optical scattering in principle, and breaks through the "soft limit" of optical imaging depth , about 1mm, can realize deep tissue living imaging with a depth of 7cm. Photoacoustic imaging not only has...

AI Technical Summary

Problems solved by technology

However, photoacoustic computed tomography has disadvantages such as long scanning time, low resolution and limited detection angle.

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