A composition of probiotic fermented angelica and its application in cosmetics

A technology of probiotics and composition, applied in the field of cosmetics, can solve the problems of undiscovered extraction of Angelica sinensis, and achieve the effects of promoting metabolism, improving SOD enzyme activity, and increasing soluble solids

Active Publication Date: 2021-05-28
SANZHU FUER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the prior art, traditional methods of water extraction, alcohol precipitation or resin purification are used to extract and process Angelica sinensis to obtain Angelica sinensis extract, but no method for extracting Angelica sinensis using biological fermentation technology has been found.

Method used

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  • A composition of probiotic fermented angelica and its application in cosmetics
  • A composition of probiotic fermented angelica and its application in cosmetics
  • A composition of probiotic fermented angelica and its application in cosmetics

Examples

Experimental program
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Effect test

Embodiment 1

[0024] Embodiment 1: Preparation of composition A of probiotic fermented Angelica sinensis

[0025] Take 100g of dried angelica, crush it through a 100-mesh sieve, add 10 times the weight of angelica powder, soak in pure water for 60 minutes, heat at 90°C for 80 minutes, when the temperature drops to 65°C, adjust the pH value to 5.0, add 300mg of cellulase , after enzymolysis at 65°C for 3 hours, heating to boiling for 10 minutes, adjusting the pH value to 6.5, and sterilizing under high temperature and high pressure at 115°C for 40 minutes to obtain the fermented angelica substrate. When the temperature drops to 39°C, insert the pre-cultured Bifidobacterium bifidum (isolated from normal human body, identified by the Institute of Microbiology, Chinese Academy of Sciences) and Bifidobacterium breve (AS 1.2213) bacteria solution, the inoculation amount is 0.5% ( volume / volume). After 5 hours of fermentation, the pre-cultured Lactobacillus acidophilus (AS1.1854) and Lactobacillu...

Embodiment 2

[0026] Embodiment 2: the preparation of the composition B of angelica sinensis fermented with probiotics

[0027] Take 140g of dried angelica, crush it through a 100-mesh sieve, add 10 times the weight of angelica powder, soak in pure water for 60 minutes, heat at 60°C for 120 minutes, when the temperature drops to 65°C, adjust the pH value to 5.0, add 280mg of cellulase , after enzymatic hydrolysis at 65°C for 3 hours, heated to boiling for 10 minutes, adjusted to pH 6.5, and sterilized under high temperature and high pressure at 115°C for 40 minutes to obtain a fermented angelica substrate. When the temperature drops to 39°C, insert the pre-cultured Streptococcus thermophilus (AS1.1855) and Lactococcus lactis subsp. lactis (AS1.2030) bacteria solution, and the inoculation volume is 0.5% (volume / volume). After 7 hours of fermentation, pre-cultured Lactobacillus delbrueckii (isolated from normal human body) and Lactobacillus rhamnosus (AS 1.26) were inoculated, and the inocula...

Embodiment 3

[0028]Example 3: Preparation of Composition C of Angelica sinensis fermented by probiotics

[0029] Take 120g of dried angelica, crush it through a 100-mesh sieve, add 10 times the weight of angelica powder, soak in pure water for 60 minutes, heat at 100°C for 40 minutes, when the temperature drops to 65°C, adjust the pH value to 5.0, and add 120mg of cellulase , after enzymatic hydrolysis at 65°C for 3 hours, heated to boiling for 10 minutes, adjusted to pH 6.5, and sterilized under high temperature and high pressure at 115°C for 40 minutes to obtain a fermented angelica substrate. When the temperature drops to 39°C, insert the pre-cultured Lactococcus lactis subsp. cremoris (AS1.3920) and Bifidobacterium infantis (isolated from normal human body) bacteria solution, and the inoculum volume is 0.5% (volume / volume). After 8 hours of fermentation, pre-cultured Lactobacillus delbrueckii (isolated from normal human body) and Lactobacillus rhamnosus (AS 1.26) were inoculated, and t...

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Abstract

The invention discloses a probiotic fermented angelica composition and its application in cosmetics. The probiotic fermented angelica composition is clarified, prepared by crushing angelica, enzymolysis, probiotic fermentation, and extraction. Transparent angelica extract; its soluble solid content is higher than 7.0%; clarity and light transmittance are higher than 98%; ferulic acid content is higher than 38.27µg / mL. The composition is used as an added ingredient to make cosmetics according to known production methods. During the metabolic process, the probiotics of the present invention produce abundant enzymes to modify and transform the ingredients of Angelica sinensis, so that the macromolecular substances are converted into small molecular substances that are easy to absorb, the soluble solids are significantly increased, the clarity of the solution is significantly increased, ferulic acid content increased significantly. Nucleic acid and acidic metabolites contained in probiotics can effectively maintain the micro-ecological environment of the skin, promote the metabolism of human skin, and achieve the effects of skin care, skin nourishment and skin health.

Description

technical field [0001] The invention relates to a preparation method of a probiotic fermented angelica composition and its application in cosmetics, belonging to the technical field of cosmetics. Background technique [0002] With the progress of society, the development of science and technology and the improvement of people's living standards, green and functional cosmetics have become the direction pursued by consumers. Chinese herbal medicine has few side effects and high safety. The correct application of active ingredient extracts of Chinese herbal medicine in cosmetics has become more and more popular among consumers and has become the main trend of cosmetics research and development at home and abroad. [0003] In my country, the use of Chinese herbal medicine for beauty has a long history. A lot of information about this aspect has been accumulated in the literature, and it has been verified by people's long-term daily health care and beauty clinical practice that ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61Q19/08
CPCA61K2800/78A61K2800/85A61Q19/08A61K8/9789
Inventor 吴炳新孙筱林叶厚立褚新红吕美
Owner SANZHU FUER PHARMA
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