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Use of long-term fasting mimicking as dietary treatment for multiple myeloma and other cancers

A multiple myeloma and diet technology, applied in the functions of food ingredients, medical preparations containing active ingredients, applications, etc., can solve problems such as inappropriate treatment of multiple myeloma

Inactive Publication Date: 2018-08-28
UNIV OF SOUTHERN CALIFORNIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Multiple myeloma is often inappropriately treated with monotherapy maintenance regimens that promote resistance development

Method used

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  • Use of long-term fasting mimicking as dietary treatment for multiple myeloma and other cancers
  • Use of long-term fasting mimicking as dietary treatment for multiple myeloma and other cancers
  • Use of long-term fasting mimicking as dietary treatment for multiple myeloma and other cancers

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Embodiment Construction

[0012] Reference will now be made in detail to presently preferred compositions, embodiments and methods of the invention, which constitute the best modes presently known to the inventors for practicing the invention. The drawings are not necessarily to scale. It is to be understood, however, that the disclosed embodiments are merely exemplary of the invention, which may be embodied in various and alternative forms. Therefore, specific details disclosed herein are not to be interpreted as limiting, but merely as a representative basis for any aspect of the invention and / or as a representative basis for teaching one skilled in the art to variously employ the invention.

[0013] Except in the examples, or where otherwise expressly stated, all quantities in this specification indicating amounts of material or conditions of reaction and / or use are to be understood as modified by the word "about" describing the broadest scope of the invention. Practice within the numerical limits ...

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Abstract

A method to treating a subject with multiple myeloma includes a step of identifying a patient having multiple myeloma. A fasting mimicking and enhancing diet is administered to the subject a predetermined time period of at least 8 days. A diet package for implementing the method is also provided.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of US Provisional Application No. 62 / 277,649, filed January 12, 2016, the disclosure of which is incorporated herein by reference in its entirety. technical field [0003] In at least one aspect, the present invention is directed to methods of treating multiple myeloma with a fasting-mimicking diet. Background technique [0004] The Fasting Mimicking and Enhancing Diet (FMED) has been developed to promote the effect of fasting on the sensitization of various cancer cell types to chemotherapy (differential stress sensitization), while protecting normal cells and tissues (differential stress resistance) As well as avoiding the burden and potential malnutrition associated with fasting. Furthermore, the metabolic conditions generated by FMED can induce apoptosis in many tumor cell types independently of chemotherapy. Multiple myeloma is often inappropriately treated with monotherapy ma...

Claims

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Application Information

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IPC IPC(8): A23L33/00A61K31/69A61K31/454
CPCA61K31/454A61K31/69A61K45/06A23L33/30A23L33/40A61P35/00A61K2300/00A23V2002/00A23V2200/30A23L33/17A23L33/115A23L33/125
Inventor 瓦尔特·D·隆哥伍德林·E·赖特
Owner UNIV OF SOUTHERN CALIFORNIA
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