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Compound essential oil composition, its application and products for alleviating depression

A technology of compound essential oils and compositions, which is applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve problems such as poor antidepressant effects and lack of scientificity in the selection or proportion of components. Achieve the effect of high acceptance of aroma crowd, synergistic anti-depressant effect, and less allergies

Active Publication Date: 2021-04-02
北京斯利安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current antidepressant essential oils have poor antidepressant effects due to the lack of scientific selection or ratio of components

Method used

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  • Compound essential oil composition, its application and products for alleviating depression
  • Compound essential oil composition, its application and products for alleviating depression
  • Compound essential oil composition, its application and products for alleviating depression

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0075] The preparation method of the present invention is to directly mix grapefruit oil, citrus oil, and bergamot oil according to volume parts, which is a method well known to those skilled in the art, and the present invention does not limit it.

[0076] Or combine grapefruit oil, citrus oil, bergamot oil with marjoram oil, cinnamon oil, clove bud oil, thyme oil, frankincense oil, lemon oil, rose oil, sweet orange oil, helichrysum oil, clary sage oil, Three or more of Roman chamomile oil and spearmint oil can be directly mixed according to the volume, which is a method well known to those skilled in the art, and the present invention is not limited thereto.

[0077] The present invention provides an application of the composition described in any one of the above technical solutions in the preparation of products for relieving depression.

[0078] The present invention provides a product for relieving depression, including the composition described in any one of the above t...

Embodiment 1～7

[0083] Embodiment 1~7; Comparative example 1~6

[0084] A compound essential oil, comprising components in parts by volume as shown in the table below.

[0085]

[0086]

[0087]

[0088]

[0089] In order to further prove the advantages of the present invention, the present invention provides the effect verification data of Examples 1-7 and Comparative Examples 1-6.

[0090] 1. Antidepressant effect verification of Examples 1-7 and Comparative Examples 1-6

[0091] The antidepressant effects of Examples 1-7 and Comparative Examples 1-6 were studied by using the mouse forced swimming test or the mouse tail suspension test.

[0092] SPF grade male Kunming mice were selected as the test subjects, and the mice were randomly divided into 14 groups, with 10 mice in each group. After 3 days of adaptive feeding, the mice were put into 600*400*200mm fresh-keeping boxes for smelling, among which Group 1 is a blank control group, put in 100 μL of distilled water; Groups 2 ...

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Abstract

The invention provides a compound essential oil composition which is prepared from the following components in parts by volume: 1 to 4 of grapefruit oil, 1 to 5 of tangerine oil and 1 to 3 of bergamotoil. According to the compound essential oil composition, through reasonable blending of stostes of purely natural essential oil such as the grapefruit oil, the tangerine oil and the bergamot oil andby combination of specific proportions, the obtained compound essential oil has a good synergetic anti-depression effect, and the audience acceptance of the fragrance is high. In addition, the compound essential oil provided by the invention does not contain artificially synthesized essence, preservatives, mineral oil and chemical allergy-causing components, is safe in component, and can hardly cause allergy.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine health care, in particular to a compound essential oil composition, its application and a product for alleviating depression. Background technique [0002] Depression is a kind of mental disease. The clinical manifestations of most patients are depression, slow thinking, loss of appetite, loss of willpower, fatigue, night sweats, loss of libido, haggard face, etc. A few patients show sudden increase in weight or appetite, insomnia, etc. or sleep more. With the increasingly intensified social competition, the accelerated pace of life, and the inability to relieve multiple pressures, more and more people are suffering from depression, the age of onset is decreasing year by year, and the patient group is expanding year by year, which seriously affects people's physical and mental health. And life happiness, but also brought a heavy burden to the whole society. [0003] Depressi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61P25/24
CPCA61K36/28A61K36/324A61K36/53A61K36/534A61K36/537A61K36/54A61K36/63A61K36/738A61K36/752A61K2300/00
Inventor 刘月帅易斌王曙宾罗丽莲肖艳皎田军
Owner 北京斯利安药业有限公司
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