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Application of petrea volubilis and extracts thereof in the aspect of preparing medicine for treating and/or preventing lung cancer

A technology of sycamore and its extract, which is applied in the field of pharmaceutical application, can solve the problems that there is no sycamore and its extract, and achieve the effect of obvious inhibitory effect

Pending Publication Date: 2018-06-29
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no report on the application of safflower and its extracts in the preparation of drugs for the treatment and / or prevention of lung cancer

Method used

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  • Application of petrea volubilis and extracts thereof in the aspect of preparing medicine for treating and/or preventing lung cancer
  • Application of petrea volubilis and extracts thereof in the aspect of preparing medicine for treating and/or preventing lung cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The preparation of embodiment 1 the water extract of tinea vulgaris

[0027] Take 200 g of the pulverized Cinnamon officinalis powder, add 5000 mL of pure water each time, decoct at 100 ° C for 1 h, repeat 3 times, combine the obtained extracts for 3 times, and concentrate them into water extract extract, so that each 1 g of water extract is soaked. The amount of crude drug contained in the paste is 7.0771g.

Embodiment 2

[0028] The preparation of embodiment 2 the alcohol extract of Cinnamon

[0029] Take 100 g of the pulverized Cinnamon officinalis powder, add 2500 mL each time, 50% ethanol, reflux in a water bath at 80°C for 1 hour, repeat 3 times, combine the three times the obtained extracts, and concentrate to obtain the ethanolic extract of C. 1g of alcohol extract contains 6.9638g of crude drugs.

Embodiment 3

[0030] Embodiment 3 Preparation of ethyl acetate extract and n-butanol extract of P.

[0031] Take the alcohol extract extract obtained in Example 2, disperse it in 50% ethanol, continuously extract 15 times with ethyl acetate, 50 mL each time, and combine the extracts to obtain the ethyl acetate extract extract of P. The n-butanol was continuously extracted 15 times, 50 mL each time, and the extracts were combined to obtain the n-butanol extract of S. Subsequently, it was concentrated at 80°C, so that 1 g of the ethyl acetate extract contains 52.0833 g of crude drugs, and 1 g of the n-butanol extract contains 41.6667 g of crude drugs.

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Abstract

The invention relates to the field of medicine application and especially provides an application of petrea volubilis and extracts thereof of preparing medicine for treating and / or preventing lung cancer. The petrea volubilis extracts are one or more selected from: a petrea volubilis water extract, a petrea volubilis alcohol extract, a petrea volubilis ethyl acetate extract and a petrea volubilisn-butanol extract. The inhibition effect on lung cancer cells by the petrea volubilis extracts is significantly better than that of other types of extracts. When the action concentration of the petreavolubilis alcohol extract is 80-160 mg / L, the inhibition effect on lung cancer cells is equal to even better than cis-platinum.

Description

technical field [0001] The present invention relates to the field of medicine application, in particular to the application of tinba vine and its extract in preparing medicines for treating and / or preventing lung cancer. Background technique [0002] The tin leaf vine is the root of Tetracera asiatica (Lour.) Hoogland of the family of twigs. It is cool in nature, bitter in taste, and has the functions of astringent and antidiarrheal, swelling and pain relief. It is commonly used in the treatment of diarrhea, dysentery, and rectal prolapse. Its medicinal materials are rich in tannins, flavonoids, terpenoids and other biologically active ingredients, which have obvious antibacterial, anti-inflammatory, anti-tumor and other activities [State Administration of Traditional Chinese Medicine Chinese Materia Medica Committee. Chinese Materia Medica [M ]. Volume 3. Shanghai: Shanghai Science and Technology Press, 1999: 510-511.]. It is rich in medicinal resources and is produced i...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P35/00
CPCA61K36/185
Inventor 朱华笪舫芳何瑞婷戴忠华樊柳园
Owner GUANGXI UNIV OF CHINESE MEDICINE
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