Multipole bidirectional high-voltage steep-sided pulse discharge system and discharge method

Abstract

The invention provides a multipole bidirectional high-voltage steep-sided pulse discharge system. The multipole bidirectional high-voltage steep-sided pulse discharge system comprises a control end, ahigh-voltage module, a pulse generating module, an electrode combined control module and at least two discharge electrode needles, wherein the control end controls the high-voltage module, the pulsegenerating module and the electrode combined control module, the pulse generating module generates positive and negative pulse, the discharge electrode needles are connected with the electrode combined control module, during the discharge process, the continuous and alternating conversion discharge of the positive and negative electrodes between each two electrodes of the discharge electrode needles is realized. For the multipole bidirectional high-voltage steep-sided pulse discharge system, the bidirectional pulse discharge among the discharge electrode needles is realized, the effective irreversible electric field wraps the tumor tissue as far as possible, the ablation blind area is reduced, and the effectiveness of the treatment plan is enhanced.

Description

technical field [0001] The invention belongs to the technical field of medical equipment for treating tumors, and in particular relates to a multi-pole bidirectional high-voltage steep pulse discharge system. Background technique [0002] Irreversible electroporation (IRE) is an emerging technology for non-thermal ablation of tumors. This technology sends a set of high-voltage electrical pulses through electrodes to form an electric field in the tissue, causing irreversible electroporation of the cell membrane, thereby causing tumor cell apoptosis. [0003] Irreversible electroporation (IRE) has emerged as an emerging modality for non-thermal treatment of tumors and other noncancerous pathologies. This solution transmits a series of short and strong electrical pulses through electrodes directly implanted or placed around the diseased tissue, forming an electric field between the electrodes and changing the transmembrane potential of the cell membrane. Once the transmembrane...

AI Technical Summary

Problems solved by technology

In clinical treatment, due to the non-uniform distribution of electric field strength in the tissue, it leads to excessive discharge treatment of cells close to the anode in clinical treatment, and incomplete treatment of cells close to the cathode.

[0005] At the same time, traditional irreversible electroporation equipment usually only has two electrodes, that is, only two-electrode discharge mode can be used. For large or irregular tumor tissues, the high-voltage electric field cannot effectively cover, which will lead to incomplete ablation or In clinical practice, multiple repeated discharges are required to achieve the desired effect

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