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Method for removing glucocorticoid in water

A glucocorticoid and water removal technology, applied in chemical instruments and methods, water pollutants, water/sewage treatment, etc., can solve the problem of inability to completely remove glucocorticoids, lack of effective glucocorticoid removal, and increase Risks and other issues, to achieve the effect of great industrial application prospects, good removal effect, simple and easy reaction device and operation

Inactive Publication Date: 2018-06-19
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Piram et al. analyzed the concentration of glucocorticoids in the influent and effluent of a sewage treatment plant in France and found that the concentrations of cortisone, hydrocortisone, budesonide and fluocinolone in the effluent (3 to 229 ng per liter) were all high The analysis reason may be that the combined glucocorticoids are cracked under the conditions of the sewage treatment process to form free glucocorticoids with strong activity, which leads to an increase in the concentration of effluent and further increases the impact of glucocorticoids on the influent water. environmental risk
[0004] In general, most studies have shown that the concentration of glucocorticoids in environmental water bodies and sewage treatment plant influent and effluent water is relatively high, some reaching hundreds or even thousands of nanograms per liter, while the existing traditional biological treatment process It is impossible to completely remove glucocorticoids, and it will even further increase the risk of glucocorticoids to the environment. Considering the toxicity and accumulation of glucocorticoids, before the effluent of sewage treatment plants is discharged into environmental water bodies or reused as reclaimed water, as well as surface water Before groundwater or groundwater is used as drinking water, glucocorticoid pollutants must be effectively removed to ensure ecological safety and human health
However, there is currently a lack of research on methods for effectively removing glucocorticoids. It is necessary to find an effective method to degrade glucocorticoids and control glucocorticoid pollution.

Method used

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  • Method for removing glucocorticoid in water
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  • Method for removing glucocorticoid in water

Examples

Experimental program
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Effect test

Embodiment 1

[0028] A method for removing glucocorticoids from water:

[0029] Firstly, the glucocorticoid solutions containing fluocinolone, triamcinolone acetonide and clobetasol propionate with concentrations of 50mg / L were prepared, the initial pH was 6.8, and the discharge voltage was adjusted to 22.4kV, 27.6kV, 30.0kV and 33.2kV, Reaction 15 to 120 minutes, the removal rates of three target glucocorticoids under different discharge voltages in different time are as follows: Figure 1-3 As shown, the removal rate of target pollutants increases with the increase of discharge voltage and the prolongation of discharge time. The discharge voltage is 27.6kV, after 120 minutes of reaction. The removal rates of the three target pollutants all reached more than 70%.

Embodiment 2

[0031] A method for removing glucocorticoids from water:

[0032] On the basis of embodiment 1, select discharge voltage to be 27.6kV, adjust initial solution pH to be 3.3, 4.6, 6.8 and 8.0 respectively, the removal rate of three kinds of target glucocorticoids after reaction 120 minutes is as follows Figure 4-6 As shown, the removal rate of clobetasol propionate has little change with pH, ​​the removal rate of fluocinolone is the highest under neutral conditions, and there is a certain inhibitory effect under acidic conditions, and the inhibitory effect increases with the increase of acidic conditions, alkali It has obvious inhibitory effect, but finally can reach 65% removal rate. Triamcinolone acetonide and fluocinolone are similar, and the removal rate is higher under neutral conditions. The stronger the acidity, the stronger the inhibitory effect. The difference is that the alkali Triamcinolone acetonide has a relatively high removal rate under aggressive conditions.

Embodiment 3

[0034] A method for removing glucocorticoids from water:

[0035]On the basis of embodiment 1, select discharge voltage to be 27.6kV, adopt respectively deionized water, ground water, tap water, surface water and secondary settling tank effluent to prepare the solution containing three kinds of target glucocorticoids, react five kinds after 120 minutes The removal rates of the three target glucocorticoids in different water matrices are as follows: Figure 7-9 shown. Under different water matrix conditions, the removal rate of the three target glucocorticoids can reach more than 67% after 120 minutes of reaction, and the surface water is more conducive to the removal of triamcinolone acetonide and clobetasol propionate. The method is applicable to the removal of glucocorticoids in different water bodies.

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Abstract

The invention discloses a method for removing glucocorticoid in water. The method is characterized by comprising the following steps: adding a solution containing target glucocorticoid into a double-dielectric barrier discharge device; adjusting discharge voltage to 22.4 to 33.2kV and reaction time to 15 to 120min; oxidizing to remove various glucocorticoids in a water matrix. Compared with the prior art, the method disclosed by the invention has the advantages that an applicable target object range is wide, a reaction device is simple and feasible to operate, an applicable environment mediumrange is wide, reaction conditions are simple and moderate, the treatment time is short, the treatment effect is good, no secondary pollution is caused, an industrial application prospect is great andthe like.

Description

technical field [0001] The invention relates to a treatment method for an environmental medium containing glucocorticoid pollutants, in particular to a method for removing glucocorticoids in water by using advanced oxidation technology of dielectric barrier discharge plasma. Background technique [0002] Glucocorticoids are a class of steroid hormones secreted by the adrenal cortex, and can also be artificially synthesized by chemical methods. Natural and synthetic glucocorticoids have the function of regulating the biosynthesis and metabolism of sugar, fat and protein. Due to their important physiological functions, they can also be used for diseases that are beyond the reach of general antibiotics or anti-inflammatory drugs, such as SARS, sepsis, etc., thereby It is widely used in the treatment of allergies, skin diseases, asthma, colitis, arthritis and other related diseases, and is one of the most clinically used drugs. Glucocorticoids have relatively stable physical an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C02F1/46C02F1/72C02F101/34
CPCC02F1/4608C02F1/72C02F2101/34
Inventor 刘亚男沈雪张艾张晗殷雪妍郝思宇李振宇高小婷王慈浩叶婷婷李响
Owner DONGHUA UNIV
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